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ResearchFormerly WizWand

Signal Peptide prediction on SignalP

0.997ROC AUCAll-pos MLM+JEPA
0.709960.784480.8590.93352May 8, 2026
Updated 6mo ago

Evaluation results

MethodLinks
All-pos MLM+JEPABackbone=ESM2-150M2026.050.997
All-pos MLM+JEPABackbone=ESM2-35M2026.050.996
MLM-onlyBackbone=AMPLIFY-120M2026.050.996
Masked-posBackbone=AMPLIFY-120M2026.050.996
All-pos MLM+JEPABackbone=Rand-Init-35M2026.050.996
Masked-posBackbone=Rand-Init-35M2026.050.996
Masked-posBackbone=ProteinBERT2-35M2026.050.996
MLM-onlyBackbone=ESM2-35M2026.050.995
Masked-pos (AdamW)Backbone=ESM2-35M2026.050.995
Masked-pos (SGDm)Backbone=ESM2-35M2026.050.995
Masked-pos (run 1)Backbone=ESM2-150M2026.050.995
MLM-onlyBackbone=Rand-Init-35M2026.050.995
MLM+JEPA @90kBackbone=Not specified2026.050.995
ProteinBERT2-150M masked-posBackbone=Not specified2026.050.995
BaselineBackbone=ESM2-35M2026.050.994
BaselineBackbone=ESM2-150M2026.050.994
MLM-onlyBackbone=ESM2-150M2026.050.994
Masked-pos (run 2)Backbone=ESM2-150M2026.050.994
BaselineBackbone=AMPLIFY-120M2026.050.993
All-pos MLM+JEPABackbone=AMPLIFY-120M2026.050.993
EMA (4h)Backbone=ESM2-150M2026.050.993
All-pos MLM+JEPABackbone=ProteinBERT2-35M2026.050.96
JEPA-onlyBackbone=ESM2-35M2026.050.956
JEPA-onlyBackbone=Rand-Init-35M2026.050.938
JEPA-only @90kBackbone=Not specified2026.050.938
ESM2-150M rand-init MLM-onlyBackbone=Not specified2026.050.933
MLM-onlyBackbone=ProteinBERT2-35M2026.050.919
BaselineBackbone=Rand-Init-35M2026.050.912
BaselineBackbone=ProteinBERT2-35M2026.050.902
JEPA-onlyBackbone=ESM2-150M2026.050.869
JEPA-onlyBackbone=AMPLIFY-120M2026.050.756
JEPA-onlyBackbone=ProteinBERT2-35M2026.050.721