# Signal Peptide prediction on SignalP Source: [Signal Peptide prediction on SignalP]() Collection index: [llms.txt]() Data updated: 2026-05-11T09:50:27.846Z Evaluation of Signal Peptide prediction performance on the SignalP dataset, reporting ROC-AUC. A research result applies to its stated dataset, split, metric and evaluation configuration. Compare like-for-like settings, preserve the metric's unit and direction, and distinguish paper-reported results from independent reproduction. The best result recorded here is not a claim of exhaustive, current global coverage. | Scope | Recorded value | | --- | --- | | Task | Signal Peptide prediction | | Dataset (including any stated split) | SignalP | | Metric | ROC AUC | | Unit | SCALAR | | Direction | Higher is better | | Results loaded | 32 of 32 | | Coverage | All results currently returned for this benchmark | Evaluation settings may differ between results. The original papers and recorded configurations are needed to establish comparability. A shared metric name alone does not establish an identical protocol. ## Metrics - [ROC AUC](): Higher is better; unit: SCALAR. ## Recorded results | Method | ROC AUC | Result date | Report paper | | --- | --- | --- | --- | | All-pos MLM+JEPA | 0.997 | Not recorded | 6a0162b1dbc836b87d823279 | | All-pos MLM+JEPA | 0.996 | Not recorded | 6a0162b1dbc836b87d823279 | | MLM-only | 0.996 | Not recorded | 6a0162b1dbc836b87d823279 | | Masked-pos | 0.996 | Not recorded | 6a0162b1dbc836b87d823279 | | All-pos MLM+JEPA | 0.996 | Not recorded | 6a0162b1dbc836b87d823279 | | Masked-pos | 0.996 | Not recorded | 6a0162b1dbc836b87d823279 | | Masked-pos | 0.996 | Not recorded | 6a0162b1dbc836b87d823279 | | MLM-only | 0.995 | Not recorded | 6a0162b1dbc836b87d823279 | | Masked-pos (AdamW) | 0.995 | Not recorded | 6a0162b1dbc836b87d823279 | | Masked-pos (SGDm) | 0.995 | Not recorded | 6a0162b1dbc836b87d823279 | | Masked-pos (run 1) | 0.995 | Not recorded | 6a0162b1dbc836b87d823279 | | MLM-only | 0.995 | Not recorded | 6a0162b1dbc836b87d823279 | | MLM+JEPA @90k | 0.995 | Not recorded | 6a0162b1dbc836b87d823279 | | ProteinBERT2-150M masked-pos | 0.995 | Not recorded | 6a0162b1dbc836b87d823279 | | Baseline | 0.994 | Not recorded | 6a0162b1dbc836b87d823279 | | Baseline | 0.994 | Not recorded | 6a0162b1dbc836b87d823279 | | MLM-only | 0.994 | Not recorded | 6a0162b1dbc836b87d823279 | | Masked-pos (run 2) | 0.994 | Not recorded | 6a0162b1dbc836b87d823279 | | Baseline | 0.993 | Not recorded | 6a0162b1dbc836b87d823279 | | All-pos MLM+JEPA | 0.993 | Not recorded | 6a0162b1dbc836b87d823279 | | EMA (4h) | 0.993 | Not recorded | 6a0162b1dbc836b87d823279 | | All-pos MLM+JEPA | 0.96 | Not recorded | 6a0162b1dbc836b87d823279 | | JEPA-only | 0.956 | Not recorded | 6a0162b1dbc836b87d823279 | | JEPA-only | 0.938 | Not recorded | 6a0162b1dbc836b87d823279 | | JEPA-only @90k | 0.938 | Not recorded | 6a0162b1dbc836b87d823279 | | ESM2-150M rand-init MLM-only | 0.933 | Not recorded | 6a0162b1dbc836b87d823279 | | MLM-only | 0.919 | Not recorded | 6a0162b1dbc836b87d823279 | | Baseline | 0.912 | Not recorded | 6a0162b1dbc836b87d823279 | | Baseline | 0.902 | Not recorded | 6a0162b1dbc836b87d823279 | | JEPA-only | 0.869 | Not recorded | 6a0162b1dbc836b87d823279 | | JEPA-only | 0.756 | Not recorded | 6a0162b1dbc836b87d823279 | | JEPA-only | 0.721 | Not recorded | 6a0162b1dbc836b87d823279 | ### All-pos MLM+JEPA ROC AUC: 0.997. Result ID: 6a01a66247f34ce924e3f85c. [Reporting paper]() [Method origin paper]() Recorded evaluation configuration: {"Backbone":"ESM2-150M"}. This record does not assert independent reproduction. ### All-pos MLM+JEPA ROC AUC: 0.996. Result ID: 6a01a66247f34ce924e3f856. [Reporting paper]() [Method origin paper]() Recorded evaluation configuration: {"Backbone":"ESM2-35M"}. This record does not assert independent reproduction. ### MLM-only ROC AUC: 0.996. Result ID: 6a01a66247f34ce924e3f860. [Reporting paper]() Recorded evaluation configuration: {"Backbone":"AMPLIFY-120M"}. This record does not assert independent reproduction. ### Masked-pos ROC AUC: 0.996. Result ID: 6a01a66247f34ce924e3f863. [Reporting paper]() [Method origin paper]() Recorded evaluation configuration: {"Backbone":"AMPLIFY-120M"}. This record does not assert independent reproduction. ### All-pos MLM+JEPA ROC AUC: 0.996. Result ID: 6a01a66247f34ce924e3f867. [Reporting paper]() [Method origin paper]() Recorded evaluation configuration: {"Backbone":"Rand-Init-35M"}. This record does not assert independent reproduction. ### Masked-pos ROC AUC: 0.996. Result ID: 6a01a66247f34ce924e3f868. [Reporting paper]() [Method origin paper]() Recorded evaluation configuration: {"Backbone":"Rand-Init-35M"}. This record does not assert independent reproduction. ### Masked-pos ROC AUC: 0.996. Result ID: 6a01a66247f34ce924e3f86d. [Reporting paper]() [Method origin paper]() Recorded evaluation configuration: {"Backbone":"ProteinBERT2-35M"}. This record does not assert independent reproduction. ### MLM-only ROC AUC: 0.995. Result ID: 6a01a66247f34ce924e3f854. [Reporting paper]() Recorded evaluation configuration: {"Backbone":"ESM2-35M"}. This record does not assert independent reproduction. ### Masked-pos (AdamW) ROC AUC: 0.995. Result ID: 6a01a66247f34ce924e3f857. [Reporting paper]() [Method origin paper]() Recorded evaluation configuration: {"Backbone":"ESM2-35M"}. This record does not assert independent reproduction. ### Masked-pos (SGDm) ROC AUC: 0.995. Result ID: 6a01a66247f34ce924e3f858. [Reporting paper]() [Method origin paper]() Recorded evaluation configuration: {"Backbone":"ESM2-35M"}. This record does not assert independent reproduction. ### Masked-pos (run 1) ROC AUC: 0.995. Result ID: 6a01a66247f34ce924e3f85d. [Reporting paper]() [Method origin paper]() Recorded evaluation configuration: {"Backbone":"ESM2-150M"}. This record does not assert independent reproduction. ### MLM-only ROC AUC: 0.995. Result ID: 6a01a66247f34ce924e3f865. [Reporting paper]() Recorded evaluation configuration: {"Backbone":"Rand-Init-35M"}. This record does not assert independent reproduction. ### MLM+JEPA @90k ROC AUC: 0.995. Result ID: 6a01a66247f34ce924e3f86e. [Reporting paper]() [Method origin paper]() Recorded evaluation configuration: {"Backbone":"Not specified"}. This record does not assert independent reproduction. ### ProteinBERT2-150M masked-pos ROC AUC: 0.995. Result ID: 6a01a66247f34ce924e3f870. [Reporting paper]() [Method origin paper]() Recorded evaluation configuration: {"Backbone":"Not specified"}. This record does not assert independent reproduction. ### Baseline ROC AUC: 0.994. Result ID: 6a01a66247f34ce924e3f853. [Reporting paper]() Recorded evaluation configuration: {"Backbone":"ESM2-35M"}. This record does not assert independent reproduction. ### Baseline ROC AUC: 0.994. Result ID: 6a01a66247f34ce924e3f859. [Reporting paper]() Recorded evaluation configuration: {"Backbone":"ESM2-150M"}. This record does not assert independent reproduction. ### MLM-only ROC AUC: 0.994. Result ID: 6a01a66247f34ce924e3f85a. [Reporting paper]() Recorded evaluation configuration: {"Backbone":"ESM2-150M"}. This record does not assert independent reproduction. ### Masked-pos (run 2) ROC AUC: 0.994. Result ID: 6a01a66247f34ce924e3f85e. [Reporting paper]() [Method origin paper]() Recorded evaluation configuration: {"Backbone":"ESM2-150M"}. This record does not assert independent reproduction. ### Baseline ROC AUC: 0.993. Result ID: 6a01a66247f34ce924e3f85f. [Reporting paper]() Recorded evaluation configuration: {"Backbone":"AMPLIFY-120M"}. This record does not assert independent reproduction. ### All-pos MLM+JEPA ROC AUC: 0.993. Result ID: 6a01a66247f34ce924e3f862. [Reporting paper]() [Method origin paper]() Recorded evaluation configuration: {"Backbone":"AMPLIFY-120M"}. This record does not assert independent reproduction. ### EMA (4h) ROC AUC: 0.993. Result ID: 6a01a66247f34ce924e3f872. [Reporting paper]() Recorded evaluation configuration: {"Backbone":"ESM2-150M"}. This record does not assert independent reproduction. ### All-pos MLM+JEPA ROC AUC: 0.96. Result ID: 6a01a66247f34ce924e3f86c. [Reporting paper]() [Method origin paper]() Recorded evaluation configuration: {"Backbone":"ProteinBERT2-35M"}. This record does not assert independent reproduction. ### JEPA-only ROC AUC: 0.956. Result ID: 6a01a66247f34ce924e3f855. [Reporting paper]() [Method origin paper]() Recorded evaluation configuration: {"Backbone":"ESM2-35M"}. This record does not assert independent reproduction. ### JEPA-only ROC AUC: 0.938. Result ID: 6a01a66247f34ce924e3f866. [Reporting paper]() [Method origin paper]() Recorded evaluation configuration: {"Backbone":"Rand-Init-35M"}. This record does not assert independent reproduction. ### JEPA-only @90k ROC AUC: 0.938. Result ID: 6a01a66247f34ce924e3f86f. [Reporting paper]() [Method origin paper]() Recorded evaluation configuration: {"Backbone":"Not specified"}. This record does not assert independent reproduction. ### ESM2-150M rand-init MLM-only ROC AUC: 0.933. Result ID: 6a01a66247f34ce924e3f871. [Reporting paper]() Recorded evaluation configuration: {"Backbone":"Not specified"}. This record does not assert independent reproduction. ### MLM-only ROC AUC: 0.919. Result ID: 6a01a66247f34ce924e3f86a. [Reporting paper]() Recorded evaluation configuration: {"Backbone":"ProteinBERT2-35M"}. This record does not assert independent reproduction. ### Baseline ROC AUC: 0.912. Result ID: 6a01a66247f34ce924e3f864. [Reporting paper]() Recorded evaluation configuration: {"Backbone":"Rand-Init-35M"}. This record does not assert independent reproduction. ### Baseline ROC AUC: 0.902. Result ID: 6a01a66247f34ce924e3f869. [Reporting paper]() Recorded evaluation configuration: {"Backbone":"ProteinBERT2-35M"}. This record does not assert independent reproduction. ### JEPA-only ROC AUC: 0.869. Result ID: 6a01a66247f34ce924e3f85b. [Reporting paper]() [Method origin paper]() Recorded evaluation configuration: {"Backbone":"ESM2-150M"}. This record does not assert independent reproduction. ### JEPA-only ROC AUC: 0.756. Result ID: 6a01a66247f34ce924e3f861. [Reporting paper]() [Method origin paper]() Recorded evaluation configuration: {"Backbone":"AMPLIFY-120M"}. This record does not assert independent reproduction. ### JEPA-only ROC AUC: 0.721. Result ID: 6a01a66247f34ce924e3f86b. [Reporting paper]() [Method origin paper]() Recorded evaluation configuration: {"Backbone":"ProteinBERT2-35M"}. This record does not assert independent reproduction. Page 1 of 1. This is an index page, not the full collection.