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Mutational effect prediction research benchmarks · SOTA2 Research

Mutational effect prediction

Benchmarks

Dataset NameSOTA MethodSort

Dataset NameSOTA methodMetricTrendResultsLast Updated

ProteinGym DMS 1 and 2 mutation set (2 mutation)

0.72Spearman Correlation

12

Mar 10, 2026

ProteinGym DMS 1 and 2 mutation set (1 mutation)

0.904Spearman Correlation

12

Mar 10, 2026

ProteinGym DMS >2 mutations set (4 mutation split)

0.615Spearman Correlation

6

Mar 10, 2026

ProteinGym DMS (>2 mutations set) (3 mutation split)

0.652Spearman Correlation

6

Mar 10, 2026

Human antibody against SARS-CoV-2 RBD (PDB ID: 7FAE) heavy chain CDR region

7.29TH31W

4

Feb 26, 2026

Popular datasets

ProteinGym Human antibody against SARS-CoV-2 RBD

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