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Mutational effect prediction on ProteinGym DMS (>2 mutations set) (3 mutation split)

0.652Spearman Correlationrd-ESM-2
0.5740.594250.61450.63475Mar 8, 2026

Evaluation results

MethodLinks
rd-ESM-2Model Scale=15B, Reverse Distillation=true2026.030.652
rd-ESM-2Model Scale=3B, Reverse Distillation=true2026.030.617
ESM-2Model Scale=15B, Reverse Distillation=false2026.030.607
ESM-2Model Scale=3B, Reverse Distillation=false2026.030.583
ESM-2Model Scale=650M, Reverse Distillation=false2026.030.578
rd-ESM-2Model Scale=650M, Reverse Distillation=true2026.030.577