Generative Enzyme Design on Enzyme Families
93.35Category 1.1.1 ScoreESM2+EGNN
Evaluation results
| Method | Links | ||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ESM2+EGNNEvaluation Protocol=AlphaFold2 pLDDT, Selection=top-5 candidate, Inverse Folding Model=ProteinMPNN2024.05 | 93.35 | — | 91.25 | 90 | 87.68 | 95.28 | 69.96 | 91.43 | 86.5 | 86.93 | 91.76 | 93.92 | 89.53 | 90.64 | 88.98 | 94.51 | 90.02 | 93.5 | 87.6 | 86.07 | 94.22 | 62.27 | 82.19 | 87.72 | 95.26 | 95.92 | 76.83 | 80.24 | 72.48 | 83.38 | 79.12 | 86.95 | |
| EnzyGenEvaluation Protocol=AlphaFold2 pLDDT, Selection=top-5 candidate, Inverse Folding Model=ProteinMPNN2024.05 | 92.85 | — | 92.68 | 90.25 | 98.04 | 98.29 | 82.15 | 93.39 | 93.34 | 95.11 | 75.91 | 98.22 | 76.31 | 91.46 | 95.7 | 94.52 | 96.8 | 98.04 | 89.22 | 81.27 | 96.82 | 71.04 | 96.64 | 98.12 | 80.57 | 80.78 | 95.23 | 80.05 | 87.88 | 93.38 | 90.87 | 90.17 | |
| RFDiffusion+IFEvaluation Protocol=AlphaFold2 pLDDT, Selection=top-5 candidate, Inverse Folding Model=ProteinMPNN2024.05 | 82.8 | — | 93.51 | 81.12 | 81.17 | 82.44 | 78.82 | 88.36 | 83.53 | 82.32 | 94.44 | 78.41 | 81.93 | 87.38 | 81.5 | 82.43 | 81.95 | 81.99 | 76.11 | 81.04 | 92.59 | 89.93 | 78.36 | 87.08 | 79.25 | 87.46 | 60.63 | 88.13 | 75.89 | 77.25 | 80.03 | 82.6 | |
| PROTSEEDEvaluation Protocol=AlphaFold2 pLDDT, Selection=top-5 candidate, Inverse Folding Model=ProteinMPNN2024.05 | 81.07 | — | 81.8 | 74.37 | 84.17 | 79.28 | 72.95 | 69.86 | 78.31 | 80.06 | 79.16 | 76.61 | 79.83 | 80.33 | 79.2 | 84.1 | 80.55 | 77.08 | 77.89 | 79.35 | 78.42 | 78.24 | 78 | 77.22 | 75.51 | 83.91 | 75.16 | 68.56 | 82.58 | 80.92 | 82.22 | 78.56 |