Enzyme structural stability prediction on BRENDA 30 EC categories (test)
91.86EC 1.1.1 Stability ScoreEnzyGen
Evaluation results
| Method | Links | |||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| EnzyGenStructural Evaluator=AlphaFold22024.05 | 91.86 | 94.4 | 93.02 | 92.7 | 91.99 | 83.47 | 87.71 | 92.81 | 87.02 | 89.69 | 89.2 | 85.19 | 87.55 | 87.64 | 91.81 | 83.75 | 89.79 | 85.4 | 89.68 | 74.44 | 77.14 | 89.11 | 86.7 | 89.8 | 85.98 | 76.31 | 84.32 | 85.71 | 91.88 | 87.55 | 87.45 | |
| EnzyGen-1.5Structural Evaluator=AlphaFold22024.05 | 91.63 | 95.19 | 92.91 | 92.6 | 89.89 | 84.95 | 86.79 | 91.12 | 87.78 | 89.21 | 88.85 | 85.12 | 86.98 | 88.18 | 91.85 | 83.46 | 90.47 | 78.29 | 88.83 | 74.84 | 76.28 | 84.29 | 87.36 | 90.58 | 87.63 | 77.12 | 86.39 | 60.65 | 92.14 | 83.1 | 86.15 | |
| ESM2+EGNNStructural Evaluator=AlphaFold22024.05 | 90.67 | 93.11 | 90.93 | 90.3 | 87.67 | 79.4 | 84.78 | 84.8 | 84.56 | 90.21 | 87.47 | 83.52 | 88.92 | 85.59 | 90.09 | 81.8 | 87.27 | 87.05 | 85.5 | 72.23 | 71.31 | 82.62 | 83.48 | 88.69 | 84.96 | 73.34 | 80.77 | 87.72 | 89.7 | 85.48 | 85.13 | |
| RFDiffusion+IFInverse folding model=ProteinMPNN, Structural Evaluator=AlphaFold22024.05 | 82.47 | 89.63 | 81.12 | 89.32 | 82.04 | 82.49 | 85.14 | 85.61 | 81.13 | 86.25 | 81.6 | 87.51 | 86.75 | 85.91 | 88.3 | 81.25 | 80.01 | 81.59 | 81.22 | 92.04 | 89.72 | 77.2 | 84.05 | 85.47 | 71.35 | 82.87 | 84.49 | 81.31 | 79.02 | 76.11 | 83.43 | |
| PROTSEEDStructural Evaluator=AlphaFold22024.05 | 77.1 | 81.8 | 71.19 | 74.24 | 78.67 | 77.4 | 74.54 | 75.18 | 77.11 | 74.79 | 75.55 | 75.9 | 81.05 | 74.05 | 76.5 | 78 | 76.29 | 77.89 | 75.75 | 78.76 | 73.56 | 82.4 | 76.7 | 75.9 | 75.16 | 74.62 | 83.46 | 76.36 | 78.87 | 83.31 | 77.07 |