Generative Enzyme Design on Enzyme-substrate 323 fourth-level categories (test) benchmark leaderboard · SOTA2 Research

Generative Enzyme Design on Enzyme-substrate 323 fourth-level categories (test)

97Average ScoreEnzyGen

Updated 5mo ago

Evaluation Results

Method	Links
EnzyGen2024.05		97	99	100	73	100	100	100	100	98	100	100	100	100	100	100	100	100	100	100	100	96	99	100	99	63	99	100	89	99	100	99
RFDiffusion+IF2024.05		94	89	95	72	58	95	68	76	95	86	95	95	95	82	95	95	98	97	93	94	92	94	97	96	60	97	97	94	92	98	97
ESM2+EGNN2024.05		94	96	97	69	97	98	98	98	97	97	97	97	97	98	98	98	98	97	93	94	92	94	97	96	60	97	97	94	92	98	97
PROTSEED2024.05		92	98	99	48	98	98	99	99	99	99	99	99	99	99	99	99	98	93	95	98	92	91	99	99	25	97	98	47	95	99	97
EnzyGen2024.05		91.34	96.49	97.81	95.67	98.2	98.6	95.38	95.16	94.18	94.88	96.8	98.49	84.15	92.73	96.03	95.67	97.82	98.51	91.55	41.93	97.35	85.52	97.3	98.55	91.58	77.43	96.18	95.08	74.63	97.86	68.76
ESM2+EGNN2024.05		84.6	96.35	97.19	88.5	92.12	96.64	77.03	95.73	94.09	94.69	96.4	96.44	93.7	94.43	92.31	97.5	93.47	97.15	89	81.39	96.87	24.73	79.01	97.69	98.18	42.35	88.55	26.98	90.32	93.36	35.89
RFDiffusion+IF2024.05		82.93	83.88	97.98	92.53	84.18	88.08	84.9	76.39	98	71.68	76.93	76.79	97.88	77.24	95.8	81.25	87.4	85.01	70.33	73.15	96.12	94.79	77.33	87.29	54.46	83.95	81.33	69.3	82.97	82.47	78.36
PROTSEED2024.05		80.97	86.28	82.47	73.36	86.48	91.38	64.9	91.83	74.33	89.81	74.43	72.72	79.61	78.34	70.53	92.71	92.04	77.49	79.17	80.26	76.65	96.63	74.94	79.85	66.33	80	82.03	86.16	83.35	85.18	79.94