Enzyme-substrate binding affinity on BRENDA 30 EC categories (test)
-8.44EC 1.1.1 ScoreEnzyGen
Evaluation Results
| Method | Links | |||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| EnzyGenEvaluation software=Gnina2024.05 | -8.44 | -4.58 | -5.1 | -10.34 | -6.95 | -10.05 | -9.89 | -9.65 | -11.91 | -9.98 | -8.05 | -10.5 | -11.65 | -12.51 | -11.24 | -8.86 | -7.01 | -8.89 | -11.9 | -10.5 | -10.6 | -10.49 | -6.37 | -6.84 | -9.23 | -13.1 | -11.35 | -11.03 | -5.51 | -10.64 | -9.44 | |
| EnzyGen-1.5Evaluation software=Gnina2024.05 | -7.63 | -5.26 | -5.87 | -10.33 | -7.87 | -11.11 | -10.61 | -10.91 | -11.84 | -9.19 | -7.46 | -9.71 | -11.65 | -12.1 | -12.57 | -9.55 | -6.67 | -8.64 | -12.01 | -11.41 | -10.14 | -10.74 | -6.72 | -6.38 | -9.1 | -12.15 | -12.39 | -10.38 | -6.04 | -10.88 | -9.58 | |
| RFDiffusion+IFEvaluation software=Gnina, Inverse folding model=ProteinMPNN2024.05 | -7.11 | -4.43 | -4.7 | -10.74 | -7.21 | -9.61 | -10.04 | -7.93 | -10.64 | -7.84 | -6.19 | -8.55 | -10.6 | -10.44 | -12.18 | -8.5 | -6.51 | -7.7 | -11.65 | -10.08 | -9.29 | -9.03 | -5.54 | -5.94 | -9.07 | -11.12 | -9.87 | -11.24 | -4.88 | -9.68 | -8.57 | |
| ESM2+EGNNEvaluation software=Gnina2024.05 | -6.66 | -4.47 | -4.81 | -10.73 | -7.02 | -9.57 | -9.98 | -8.61 | -10.9 | -7.95 | -6.43 | -8.79 | -10.23 | -10.75 | -11.31 | -8.47 | -5.81 | -7.2 | -11.45 | -10.14 | -8.91 | -9.25 | -5.59 | -5.42 | -8.23 | -10.69 | -11.15 | -11.34 | -5.01 | -9.76 | -8.52 | |
| PROTSEEDEvaluation software=Gnina2024.05 | -6.61 | -3.93 | -4.27 | -10.22 | -6.71 | -8.84 | -9.58 | -7.43 | -10.01 | -7.44 | -5.46 | -8.07 | -9.68 | -10.24 | -11.68 | -8 | -6.01 | -7.2 | -9.16 | -9.53 | -8.79 | -8.67 | -5.19 | -5.44 | -8.57 | -10.11 | -9.37 | -9.74 | -4.38 | -9.11 | -7.94 |