Enzyme-substrate binding prediction on Enzyme Family candidates Top-10
95EC 1.1.1 PerformanceEnzyGen
Evaluation Results
| Method | Links | |||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| EnzyGenCandidate selection=top-10, Inverse folding model=ProteinMPNN2024.05 | 95 | 100 | 64 | 99 | 99 | 100 | 99 | 88 | 99 | 99 | 99 | 99 | 100 | 100 | 100 | 99 | 99 | 99 | 100 | 91 | 69 | 100 | 94 | 27 | 98 | 100 | 74 | 99 | 100 | 99 | 93 | |
| PROTSEEDCandidate selection=top-10, Inverse folding model=ProteinMPNN2024.05 | 90 | 67 | 38 | 98 | 78 | 99 | 82 | 55 | 98 | 96 | 96 | 98 | 99 | 99 | 80 | 97 | 70 | 90 | 95 | 89 | 68 | 97 | 73 | 14 | 50 | 91 | 37 | 86 | 99 | 94 | 81 | |
| ESM2+EGNNCandidate selection=top-10, Inverse folding model=ProteinMPNN2024.05 | 89 | 96 | 59 | 94 | 93 | 96 | 91 | 88 | 95 | 95 | 94 | 95 | 96 | 97 | 95 | 95 | 95 | 90 | 90 | 84 | 62 | 94 | 86 | 23 | 93 | 95 | 71 | 89 | 97 | 93 | 88 | |
| RFDiffusion+IFCandidate selection=top-10, Inverse folding model=ProteinMPNN2024.05 | 68 | 95 | 54 | 47 | 69 | 54 | 55 | 48 | 71 | 66 | 77 | 67 | 51 | 83 | 89 | 78 | 49 | 85 | 89 | 55 | 92 | 47 | 67 | 53 | 73 | 66 | 76 | 84 | 95 | 60 | 69 |