Protein Stability Change Prediction on S669
0.54Spearman CorrelationConstraint-Aware Optimization Framework
Evaluation results
| Method | Links | |
|---|---|---|
| Constraint-Aware Optimization Frameworkobjective=full three-component objective (BMC + Siamese + OOD-margin)2026.06 | 0.54 | |
| Stability Oracle2026.06 | 0.5 | |
| SPURS2026.06 | 0.5 | |
| ThermoMPNN2026.06 | 0.44 | |
| ProteinMPNN2026.06 | 0.43 | |
| ESM2026.06 | 0.37 |