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Fitness Prediction research benchmarks · SOTA2 Research

Fitness Prediction

Benchmarks

Dataset NameSOTA MethodSort

Dataset NameSOTA methodMetricTrendResultsLast Updated

ProteinGym (overall)

0.519Spearman Correlation

43

Apr 14, 2026

MaveDB subset of 50 proteins

ProSST + ProteinTTT

0.546Average Spearman Correlation

10

Mar 4, 2026

0.78Spearman Correlation (GFP Stability)

7

Feb 26, 2026

Variant Effect GB1 (test)

Masked-pos MLM+JEPA

4W/L/T Counts

1

May 11, 2026

Popular datasets

ProteinGym MaveDB Variant Effect

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