Top 100 independent loci replication on Hematopoiesis traits (MCH, IRF, RDW) GWAS sample size 50,000
229Replicated Loci CountContext-aware KGWAS (Replace with perturb graph)
Evaluation Results
| Method | Links | |
|---|---|---|
| Context-aware KGWAS (Replace with perturb graph)# Edges=625K2026.03 | 229 | |
| KGWAS + Prioritize genes# Edges=1.3M2026.03 | 226.33 | |
| KGWAS# Edges=12.1M2026.03 | 221 | |
| KGWAS + Prune edge types# Edges=3.4M2026.03 | 221 | |
| KGWAS + Remove gene programs# Edges=12.1M2026.03 | 220 | |
| KGWAS + Collapse GG edges# Edges=2.3M2026.03 | 218.67 | |
| GWAS# Edges=02026.03 | 201 |