Protein-ligand binding affinity prediction on ATOM3D LBA 60% sequence identity benchmark leaderboard · SOTA2 Research

Protein-ligand binding affinity prediction on ATOM3D LBA 60% sequence identity

1.217RMSECPES

Evaluation Results

Method	Links
CPES2026.06		1.217	0.803	0.802
CPES2026.06		1.217	0.803	0.802
BindNet2026.06		1.23	0.793	0.788
BindNet2026.06		1.23	0.793	0.788
CheapNet2026.06		1.238	0.794	0.789
CheapNet2026.06		1.238	0.794	0.789
ProNet2026.06		1.343	0.765	0.761
ProNet2026.06		1.343	0.765	0.761
Uni-Mol2026.06		1.357	0.753	0.75
Uni-Mol2026.06		1.357	0.753	0.75
Holoprot2026.06		1.365	0.749	0.742
Holoprot2026.06		1.365	0.749	0.742
ProFSA2026.06		1.377	0.764	0.762
ProFSA2026.06		1.377	0.764	0.762
Atom3D-GNN2026.06		1.408	0.743	0.743
Atom3D-GNN2026.06		1.408	0.743	0.743
IEConv2026.06		1.473	0.667	0.675
IEConv2026.06		1.473	0.667	0.675
EGNN-PLM2026.06		1.559	0.644	0.646
EGNN-PLM2026.06		1.559	0.644	0.646
TAPE2026.06		1.633	0.568	0.571
TAPE2026.06		1.633	0.568	0.571
ProtTrans2026.06		1.641	0.595	0.588
ProtTrans2026.06		1.641	0.595	0.588
DeepDTA2026.06		1.762	0.666	0.663
DeepDTA2026.06		1.762	0.666	0.663
SSA2026.06		1.891	0.249	0.275
SSA2026.06		1.891	0.249	0.275