Peptide-Protein Interaction Prediction on Propedia PPI aCSM (cluster-based)
0.7885ROC-AUCESM-2 (650M)
Evaluation results
| Method | Links | ||||
|---|---|---|---|---|---|
| ESM-2 (650M)Evaluation Protocol=MLP, Params=651M2025.12 | 0.7885 | 0.5263 | 0.3356 | 0.6989 | |
| ESM-2 (35M)Evaluation Protocol=MLP, Params=34M2025.12 | 0.7882 | 0.5282 | 0.3464 | 0.7046 | |
| ESM-2 (150M)Evaluation Protocol=MLP, Params=148M2025.12 | 0.7789 | 0.5118 | 0.3367 | 0.6971 | |
| HELM-BERTEvaluation Protocol=MLP, Params=54.2M2025.12 | 0.7713 | 0.509 | 0.3172 | 0.6873 | |
| MoLFormer–XLEvaluation Protocol=MLP, Params=44.4M2025.12 | 0.7516 | 0.4643 | 0.2938 | 0.6795 | |
| PeptideCLMEvaluation Protocol=MLP, Params=43.0M2025.12 | 0.7418 | 0.4516 | 0.2798 | 0.6712 | |
| Peptide DescriptorsEvaluation Protocol=MLP2025.12 | 0.7389 | 0.4627 | 0.2863 | 0.67 | |
| HELM-BERTEvaluation Protocol=Linear, Params=54.2M2025.12 | 0.5656 | 0.2333 | 0.0685 | 0.5414 | |
| ESM-2 (650M)Evaluation Protocol=Linear, Params=651M2025.12 | 0.5644 | 0.2276 | 0.0647 | 0.5373 | |
| ESM-2 (150M)Evaluation Protocol=Linear, Params=148M2025.12 | 0.5587 | 0.2259 | 0.059 | 0.5354 | |
| ESM-2 (35M)Evaluation Protocol=Linear, Params=34M2025.12 | 0.5517 | 0.2227 | 0.052 | 0.5317 | |
| MoLFormer–XLEvaluation Protocol=Linear, Params=44.4M2025.12 | 0.5484 | 0.2237 | 0.0599 | 0.5366 | |
| PeptideCLMEvaluation Protocol=Linear, Params=43.0M2025.12 | 0.5415 | 0.2234 | 0.0414 | 0.525 | |
| Peptide DescriptorsEvaluation Protocol=Linear2025.12 | 0.531 | 0.2117 | 0.0274 | 0.517 |