Molecular Optimization (LogP) on TOMG-Bench benchmark leaderboard · SOTA2 Research

Molecular Optimization (LogP) on TOMG-Bench

96.8Success Rate (SR)MolLingo

Evaluation Results

Method	Links
MolLingo2026.05		96.8	73	70.6
GPT-5.42026.05		87.1	61.2	53.3
OpenMolIns-large2026.05		80.54	66.78	53.8
Claude-32026.05		79.84	60.67	48.4
Claude-3.52026.05		79.7	71.24	56.8
Gemini-1.5-pro2026.05		77.12	70.22	54.2
GPT-4-turbo2026.05		76.62	69.84	53.5
OpenMolIns-xlarge2026.05		73.62	57.44	42.3
GPT-4o2026.05		71.9	65.9	47.4
OpenMolIns-large2026.05		64.54	59.27	38.3
Llama3-70B-Instruct2026.05		59.84	60.28	36.1
OpenMolIns-medium2026.05		59.04	58.12	34.3
Bio-T5-base2026.03		51.6	15.3	7.9
BioT5-base2026.05		51.58	15.26	7.9
MOLLEO2026.03		51	10.3	5.3
Graph GA2026.03		50.9	12.5	6.4
GPT-4o-mini2026.03		49.9	70.6	35.2
REINVENT2026.03		46.5	12.5	5.8
Llama3-8B-Instruct2026.05		46.42	36.58	17
MolT5-large2026.05		42.44	10.15	4.3
Mol-T5-large2026.03		42.4	10.2	4.3
OpenMolIns-small2026.05		41.72	64.2	26.8
RePO2026.03		41.5	71.5	29.7
RePO2026.05		41.5	71.5	29.7
GPT-3.5-turbo2026.05		40.48	63.27	25.6
Llama3.1-8B-Instruct2026.05		39.9	42.35	16.9
GRPO2026.03		37.9	80.6	30.5
Chatglm-9B2026.05		36.66	69.02	25.3
OpenMolIns-light2026.05		32.02	65.47	21
SFT2026.03		29.8	69.2	20.6
OpenMolIns-large2026.05		28.98	59.51	17.2
Yi-1.5-9B2026.05		28.84	54.61	15.7
Baseline2026.03		26.8	62.7	16.8
Mistral-7B-Instruct-v0.22026.05		22.2	45.01	10
MolT5-small2026.05		21.58	10.52	2.3
GRPO2026.03		21.2	86.3	18.3
MolT5-base2026.05		20.74	10.51	2.2
Llama-3.2-1B-Instruct2026.05		6.44	50.55	3.3
Qwen2-7B-Instruct2026.05		0	29.23	0