Enzyme Commission depth-1 function prediction on MISATO (structure) benchmark leaderboard · SOTA2 Research

Enzyme Commission depth-1 function prediction on MISATO (structure)

88.2Top-1 AccuracyESM3struct

Evaluation Results

Method	Links
ESM3struct2026.05		88.2	61.5	94.3	54.8	86.9	—	—
ESM3struct2026.05		88.2	61.5	—	54.8	—	94.3	86.9
AminoAseed2026.05		84.1	56.9	91.2	51.4	83	—	—
AminoAseed2026.05		84.1	56.9	—	51.4	—	91.2	83
ENSEMBITS2026.05		83.9	54.3	87.1	45.6	80	—	—
ENSEMBITS2026.05		83.9	54.3	—	45.6	—	87.1	80
Vote_3Di2026.05		77.4	50.4	81.8	42.2	76.5	—	—
Vote_3Di2026.05		77.4	50.4	—	42.2	—	81.8	76.5
ENSEMBITS2026.05		67.4	46.2	71.4	36.5	64.3	—	—
ENSEMBITS2026.05		67.4	46.2	—	36.5	—	71.4	64.3
3Di_tokens2026.05		54.8	42.9	53.3	28.8	52	—	—
3Di_tokens2026.05		54.8	42.9	—	28.8	—	53.3	52
ProToken2026.05		37.6	26.5	38.5	11.8	37.4	—	—
ProToken2026.05		37.6	26.5	—	11.8	—	38.5	37.4
ProtProfileMD_K82026.05		37.4	24.7	33	8.7	29.5	—	—
ProtProfileMD_K82026.05		37.4	24.7	—	8.7	—	33	29.5
random2026.05		36	21.2	30.5	10.8	34.7	—	—
Random2026.05		36	21.2	—	10.8	—	30.5	34.7
aa2026.05		33.3	34.6	35	8	26.6	—	—
aa2026.05		33.3	34.6	—	8	—	35	26.6