Caption-to-molecule generation on ChEBI-20 benchmark leaderboard · SOTA2 Research

Caption-to-molecule generation on ChEBI-20

59.82Exact MatchMol-Debate

Evaluation Results

Method	Links
Mol-Debate2026.04		59.82	70.59	30.8294	96.01	91.03	86.94	0.1258	99.73	—	—	—
ChemDFM-v1.5-8B2026.04		53.79	60.86	41.1333	93.88	87.98	83.14	0.1957	97.7	—	—	—
MolReFlect2024.11		51	90.3	11.84	—	—	—	—	97.7	92.9	86	81.3
ChemDFM-R-14B2026.04		49.48	67.33	33.9506	93.13	85.92	80.92	0.2236	97.33	—	—	—
ICMA2024.11		46	85.5	18.73	—	—	—	—	95.8	91.6	83.7	78.9
Chem-R-8B2026.04		43.85	86.48	16.183	92.04	83.98	78.27	0.2747	96.64	—	—	—
MSR2026.04		42.1	87.8	12.76	92.4	85.6	80.4	0.26	98.2	—	—	—
BioT5-base2026.04		41.3	86.7	15.097	88.6	80.1	73.4	0.43	100	—	—	—
BioT52024.11		41.3	86.7	15.1	—	—	—	—	100	88.6	80.1	73.4
MolT5-large2026.04		31.1	85.4	16.071	83.4	74.6	68.4	1.2	90.5	—	—	—
MolT5-large2024.11		31.1	85.4	16.07	—	—	—	—	90.5	83.4	74.6	68.4
MolReGPT2026.04		28	85.7	17.14	90.3	80.5	73.9	0.59	89.9	—	—	—
MolReGPT2024.11		28	85.7	17.14	—	—	—	—	89.9	90.3	80.5	73.9
Mol-R12026.04		23.4	64.1	32.94	82.3	68.4	61.2	—	84.7	—	—	—
GPT-5 mini2026.04		17.73	40.46	47.1945	88.29	72.8	65.75	1.2423	79.42	—	—	—
Gemma-4-31b-it2026.04		4.52	37.86	49.8358	70.67	49.32	41.69	3.808	70.61	—	—	—
Mol-Instruction2026.04		4	30	39.42	44	29	25	—	100	—	—	—
GPT-4o mini2026.04		1.73	19.47	63.2667	59.88	36.29	30.27	8.6415	51.48	—	—	—
Llama-3.1-8B-Instruct2026.04		0.45	18.73	73.8242	58.38	34.89	26.44	6.9835	41.67	—	—	—