Binding affinity prediction on SKEMPI2 single mutations benchmark leaderboard · SOTA2 Research

Binding affinity prediction on SKEMPI2 single mutations

0.672Pearson Correlation (Overall)DiffAffinity

Evaluation Results

Method	Links
DiffAffinity2023.10		0.672	0.523	1.288	0.923	0.733	0.887	0.429	0.409
DiffAffinity*2023.10		0.657	0.523	1.312	0.931	0.742	0.741	0.417	0.396
DDGPred2023.10		0.652	0.359	1.309	0.936	0.656	0.884	0.351	0.318
RDE-Net2023.10		0.637	0.491	1.341	0.961	0.72	0.885	0.413	0.385
ESM2*2023.10		0.625	0.468	1.357	0.986	0.707	0.879	0.391	0.342
flex ddG2023.10		0.425	0.431	1.457	0.997	0.677	0.874	0.433	0.435
Rosetta2023.10		0.325	0.367	1.183	0.987	0.674	0.834	0.351	0.418
DiffAffinity-Linear2023.10		0.318	0.293	1.649	1.175	0.651	0.854	0.209	0.202
FoldX2023.10		0.315	0.361	1.651	1.146	0.657	0.839	0.382	0.36
ESM-IF2023.10		0.296	0.287	1.673	1.137	0.605	0.776	0.391	0.364
ESM-1v2023.10		0.191	0.157	1.723	1.192	0.549	0.77	0.042	0.027
ESM22023.10		0.1	0.12	1.73	1.21	0.541	0.734	0.019	0.036