Antibody Binder Generation on Trastuzumab CDR H3 mutant dataset (test) benchmark leaderboard · SOTA2 Research

Antibody Binder Generation on Trastuzumab CDR H3 mutant dataset (test)

0.0074W1 (Natural)DiffAb

Evaluation Results

Method	Links
DiffAb2023.07		0.0074	0.0014	0.0498	0.5481	0.0097	0.0067	3.4647	6.7419	0.4151	0.8876	99.7
MEAN2023.07		0.0072	0.0009	0.0267	8.4184	0.0184	0.0231	0.4108	8.5981	0.7792	0.7767	38.9
FA-GNN2023.07		0.0018	0.003	0.0063	0.4158	0.0107	0.0056	0.2644	76.7852	3.18	0.4576	100
AbDiffuser2023.07		0.0015	0.0024	0.0159	1.5043	0.021	0.0126	0.5173	114.4841	0.6795	0.9436	91.4
Transformer2023.07		0.0014	0.0031	0.0097	1.3681	0.0171	0.014	0.2657	—	—	0.3627	100
EGNN2023.07		0.0013	0.003	0.0102	1.1241	0.0123	0.0236	0.2441	1,967.528	9.218	0.3626	100
AbDiffuser2023.07		0.0013	0.0018	0.0028	0.4968	0.0205	0.0113	0.1588	6.4301	0.3822	0.5761	100
Validation Set Baseline2023.07		0.0011	0.0003	0.0061	1.3183	0.0196	0.0114	0.328	2.035	—	0.8676	100
RefineGNN2023.07		0.0011	0.0004	0.0026	0.5482	0.0053	0.0046	0.126	—	—	0.7132	100
AbDiffuser2023.07		0.001	0.0005	0.0062	1.2909	0.0115	0.0029	0.0948	32.0464	0.4046	0.6848	100
AbDiffuser2023.07		0.0008	0.0014	0.0265	2.5944	0.0206	0.0053	0.2378	15.22	0.3345	0.9115	99.7
AbDiffuser2023.07		0.0005	0.0011	0.0054	0.3934	0.0148	0.0129	0.1785	6.2468	0.3707	0.6382	100
AbDiffuser2023.07		0.0005	0.0004	0.0126	1.851	0.0126	0.0017	0.0917	12.8923	0.3982	0.7796	100