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ResearchFormerly WizWand

Replogle

Benchmarks

TaskDatasetSOTA resultTrendResults

Perturbation prediction

Replogle

0.039DEOver

22

Single-cell gene expression generation

Replogle

10R2 Mean

7

Conditional cell generation

Replogle

9.311W2

7

Conditional Cell Generation

Replogle (test)

10.684W2

7

Single-cell perturbation prediction

Replogle2022 (single-gene i.i.d.)

8.296L2 Distance

5

Perturbation Prediction

Replogle genetic perturbations (unseen interventions)

0.491Pearson Correlation Coefficient

5

Single-intervention outcome prediction

REPLOGLE SMALL

0.839R2

4

Cross-cell-type generalization

Replogle perturbations (test)

0.633Pearson Correlation (DEG)

4

Single-intervention outcome prediction

REPLOGLE Large

0.849R2

3

cell reconstruction

Replogle

1,602.66RE (Reconstruction Error)

2

Gene association prediction

Replogle K562 + STRING (High confidence ≥900)

0.91AUC

2

Gene association prediction

Replogle K562 + STRING (Low confidence ≥400)

0.8AUC

2