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Companies building AI

Profiles of the teams behind AI applications, infrastructure, models and developer tools, with the products they make and where those products rank.

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3,001–3,050 of 4,902

  • OpenEvidence

    OpenEvidence is the leading medical platform for healthcare professionals, featuring answers grounded in peer-reviewed research from NEJM, JAMA, NCCN, Cochrane, and more. It is the most widely used medical AI platform among U.S. physicians.

    Healthcare & Life Sciences

  • OpenEye Scientific

    OpenEye Scientific, now part of Cadence Solutions, provides cloud-based computational chemistry software, toolkits, and drug discovery services for molecular design and virtual screening.

    Healthcare & Life Sciences

  • OpenFoundry

    Provides a developer experience for building, deploying, and scaling applications on open source AI.

    Software Development

  • OpenFunnel

    Composable, agent-ready primitives for go-to-market. Resolve, search, enrich, signal, score, and monitor accounts and people over REST.

    Sales

  • OpenGov

    AI-powered SaaS platform for U.S. government agencies spanning finance, permitting, procurement, and public works.

    Finance & Business Operations

  • OpenHack, Inc.

    Always-on AI security engineer that finds, verifies, prioritizes, and fixes vulnerabilities across codebases and live applications.

    Cybersecurity & IT

  • OpenIntake

    The complete intake platform for law firms. One fully managed AI platform answers, qualifies, and books every lead by phone, text, web chat, or form, 24/7.

    Sales

  • OpenLake

    Self-evolving infrastructure for high-performance LLM inference that learns from workloads to improve routing, batching, and execution.

    Models & AI Infrastructure

  • OpenMOPAC

    Open-source project maintaining MOPAC (Molecular Orbital PACkage), a semiempirical quantum chemistry package. MOPAC is actively maintained and curated by the Molecular Sciences Software Institute (MolSSI).

    Models & AI Infrastructure

  • OpenModelica

    Open-source Modelica-based modeling, compilation, and simulation environment intended for industrial and academic usage. Long-term development is supported by the non-profit Open Source Modelica Consortium (OSMC).

    Models & AI Infrastructure

  • OpenRelay

    A distributed GPU cloud for production workloads, described as the CDN of inference.

    Software Development

  • OpenRouter

    The unified interface for LLMs. Access all major models through a single, OpenAI-compatible API with 400+ models from 70+ providers.

    Models & AI Infrastructure

  • OpenSEO

    Open source SEO platform offering keyword research, backlinks, rank tracking, site audits, and AI visibility, billed by usage. Self-hostable or connectable to AI agents over MCP.

    Marketing & Commerce

  • OpenThai

    Free and open-source Thai large language model project operated by AIEAT (AI Entrepreneur Association of Thailand). Formerly known as OpenThaiGPT.

    Models & AI Infrastructure

  • OpenTools

    Provider of an API for LLM tool use, offering a single completions API endpoint that enables any LLM to access MCP tools.

    Models & AI Infrastructure

  • OpenWhispr

    Open-source, privacy-focused voice-to-text and meeting-notes application with local processing, offline support, AI cleanup, and cloud transcription options.

    Productivity & Collaboration

  • Openlayer

    AI governance and observability platform for evaluating, monitoring, and ensuring compliance of ML and LLM systems.

    Models & AI Infrastructure

  • Openmart

    Local business lead data platform with 200M+ verified contacts, searchable by category, zip code, or keyword, with built-in outreach automation.

    Sales

  • Opennote

    Opennote is an AI-assisted educational tool provider described as 'The notebook that thinks with you.' The company has been acquired by Reducto to build the future of document intelligence.

    Productivity & Collaboration

  • Openroll

    AI workforce platform for people and finance teams that connects to HRIS, ERP, and ATS systems, runs analyses with full auditability, and turns team expertise into agentic operations.

    Finance & Business Operations

  • Opensteer

    Platform for creating specialized AI agents that browse the web, use tools, and run on schedules in local or hosted workspaces.

    Software Development

  • Opentech

    A technology provider specializing in digital remittance, payments, and workflow automation for banks and card issuers.

    Financial Services & Insurance

  • Operator.io

    Operator.io provides an AI Chief of Staff service built on OpenClaw that automates inbox, calendar, and operational tasks. The hosted agent operates via Telegram or Discord to manage email, research, CRM updates, and monitoring alerts.

    Productivity & Collaboration

  • Operon Solutions

    Operon Solutions provides an agentic data layer for the process and manufacturing industries, ingesting engineering documents like P&IDs, isometrics, and line lists to create a live, queryable context layer for search, compliance, and AI agents.

    Data & Analytics

  • Opgal

    Manufacturer of infrared thermal cameras, optical gas imaging (OGI), and electro-optical systems for oil, gas, industrial, and defence markets, operating in over 60 countries.

    Energy, Climate & Agriculture

  • Opslane, Inc.

    Y Combinator-backed company providing automated PR verification by running code in a real browser and posting evidence — screenshots, video, and data checks — on pull requests.

    Software Development

  • Optilyx

    AI-powered optimization engine that computes best decisions under real-world constraints using non-linear, mixed-integer, multi-objective optimization with real-time GPU-accelerated search.

    Finance & Business Operations

  • Optimal Dynamics

    AI-driven Transportation Decision System (TDS) provider for truckload carriers and private fleets. Headquartered at 12 W 27th Street, Floor 12, New York, NY 10001.

    Industrial, Robotics & Mobility

  • Optro

    AI-powered GRC platform for managing risk, audit, compliance, IT security, and ESG programs. Formerly AuditBoard.

    Legal, Risk & Compliance

  • Opusense

    AI-powered inspection software for construction, engineering, and property teams. Capture in the field, generate branded reports in minutes, and turn inspection history into a searchable dataset.

    Real Estate & Construction

  • Oqton

    Software provider for additive manufacturing, operating a cloud-based, AI-enabled Manufacturing Operating System (MOS) platform. Acquired by 3D Systems in November 2021 and operates as an independent organization.

    Industrial, Robotics & Mobility

  • Ora AI

    Medical education platform for preclinical, USMLE Step, and shelf exam preparation.

    Education & Training

  • Oracle Health

    A division of Oracle Corporation providing AI-powered, cloud-based solutions including electronic health records (EHR), analytics, and clinical operations management for healthcare providers, payers, and public health organizations.

    Software Development

  • Orangewood Labs

    Builds affordable, AI-powered robotic arms that are simple to operate, safe, and capable of addressing modern manufacturing challenges.

    Industrial, Robotics & Mobility

  • Orbio Earth

    Satellite-based methane emissions monitoring for the oil & gas industry, delivering asset-level emission insights to financial and energy sectors.

    Energy, Climate & Agriculture

  • Orbital Sidekick

    Provider of hyperspectral GEOINT data and persistent monitoring solutions.

    Government & Public Safety

  • Orbits

    Orbits is an AI household assistant and home manager that handles household logistics for families.

    Customer Service

  • Orby

    Company developing non-invasive neurotechnology combining signal capture, proprietary AI, and electrical neuromodulation for functional rehabilitation and pain management.

    Healthcare & Life Sciences

  • Orca

    Minecraft mod and addon creation platform; AI builds mods from plain-English descriptions.

    Software Development

  • Orca AI

    AI-based maritime navigation platform providing computer vision and deep learning for real-time onboard perception and fleet management for commercial shipping and defense.

    Industrial, Robotics & Mobility

  • Orca Aerospace

    Orca Aerospace builds an AI spacecraft operator that flies with the vehicle, understands the mission, monitors systems, and acts when ground operations cannot.

    Models & AI Infrastructure

  • Orchard

    An agricultural technology company providing AI-powered orchard sensing systems, data management platforms, and autonomous decision-making tools to automate farm management.

    Energy, Climate & Agriculture

  • Orchid

    Orchid is a personal assistant that lives in your messages. It connects your tools, automates your workflows, and handles the busywork so you can focus on what matters.

    Productivity & Collaboration

  • Ordo Labs

    Develops Ordo, an AI workspace for regulated laboratories that drafts reports, runs SOP-defined QC checks, and traces reported values to source data.

    Productivity & Collaboration

  • Organizely

    Factory operating system for growing manufacturers that combines operational visibility, production planning, and AI-powered workflow automation.

    Industrial, Robotics & Mobility

  • Orgo

    Secure, persistent cloud computers for AI agents, providing always-on desktops where agents can work without customers setting up or maintaining servers.

    Software Development

  • OriGen AI

    New York City-based software developer offering AI solutions for the energy industry under the Proteus platform brand, providing reservoir simulation, optimization, and forecasting capabilities for enterprise customers.

    Models & AI Infrastructure

  • Origami Risk

    Purpose-built risk, safety, and insurance software delivered on a configurable cloud platform, streamlining compliance, claims, and operations for primarily companies and governmental entities.

    Legal, Risk & Compliance

  • Origin Bio

    Origin Bio maps cancer biology in real tumors by generating multimodal datasets from patient tissue, including spatial transcriptomics, morphology, proteomics, and ex vivo perturbation response data.

    Healthcare & Life Sciences

  • Original Games

    Original Games is a global developer of casual mobile games, creating relaxing and rewarding gameplay with universal appeal. The company was founded in 2019 and is backed by Play Ventures, with teams located in Tallinn, Helsinki, San Francisco, and Berlin.

    Creative & Media