Unconditional Protein Backbone Generation on PDB & AFDB (test) benchmark leaderboard · SOTA2 Research

Unconditional Protein Backbone Generation on PDB & AFDB (test)

0.995DesignabilitySaDiT

Evaluation Results

Method	Links
SaDiT2026.02		0.995	0.7534	0.31	0.58	0.61	123.5	152.6	3.52	7.21	28.68	0.52	0.83	0.523	0.036
FoldFlow2026.02		0.972	0.3718	0.41	0.71	0.75	431.4	414.1	1.35	3.1	13.62	2.9	2.32	0.827	0.02
FoldFlow2026.02		0.97	0.2512	0.44	0.74	0.78	543.6	520.4	1.21	2.09	11.59	3.69	2.71	0.861	0.012
FoldFlow2026.02		0.966	0.2098	0.45	0.75	0.79	601.5	566.2	1.06	1.79	9.72	3.18	3.1	0.875	0.004
Proteína2026.02		0.964	0.6331	0.36	0.69	0.75	388	368.2	2.06	5.32	19.05	1.65	1.23	0.681	0.069
Genie22026.02		0.952	0.5928	0.38	0.63	0.69	350	313.8	1.55	3.66	11.65	2.21	1.7	0.727	0.048
RFDiffusion2026.02		0.944	0.4622	0.42	0.71	0.77	253.7	252.4	2.25	5.06	19.83	1.21	1.13	0.643	0.172
Proteus2026.02		0.942	0.221	0.45	0.74	0.76	225.7	226.2	2.26	5.46	16.22	1.41	1.37	0.731	0.091
FrameFlow2026.02		0.886	0.5324	0.36	0.69	0.73	129.9	159.9	2.52	5.88	27	0.68	0.91	0.557	0.184
Chroma2026.02		0.748	0.5119	0.38	0.69	0.74	189	184.1	2.34	4.95	18.15	1	1.08	0.69	0.125
FrameDiff2026.02		0.654	0.3913	0.4	0.73	0.75	194.2	258.1	2.46	5.78	23.35	1.04	1.42	0.649	0.112
ESM32026.02		0.22	0.5864	0.42	0.85	0.87	933.9	855.4	3.19	6.71	17.73	1.53	0.98	0.645	0.085