Supervised protein substitution DMS prediction on ProteinGym Contig benchmark leaderboard · SOTA2 Research

Supervised protein substitution DMS prediction on ProteinGym Contig

0.7Spearman's rhoAUTOSCIENTISTS

Evaluation Results

Method	Links
AUTOSCIENTISTS2026.05		0.7	0.611
Kermut2026.05		0.657	0.605
AUTOSCIENTISTS2026.05		0.635	0.812
ProteinNPT2026.05		0.619	0.687
Kermut2026.05		0.593	0.737
MSA Transformer Embeddings2026.05		0.581	0.724
Tranception Embeddings2026.05		0.548	0.802
ESM-1v Embeddings2026.05		0.535	0.789
ProteinNPT2026.05		0.529	0.856
MSA Transformer Embeddings2026.05		0.513	0.86
ESM-1v Embeddings2026.05		0.479	0.914
Tranception Embeddings2026.05		0.439	1.037