Single-property Molecule Optimization on S^2-Bench v1.0 (test)
98.38logP SRBioMatrix-4B
Evaluation Results
| Method | Links | ||||||
|---|---|---|---|---|---|---|---|
| BioMatrix-4BModel Scale=4B, Molecule Representation=SMILES2026.06 | 98.38 | 66.25 | 97.08 | 65.02 | 83.68 | 56.72 | |
| BioMatrix-1.7BModel Scale=1.7B, Molecule Representation=SMILES2026.06 | 97.8 | 66.35 | 95.9 | 64.36 | 82.1 | 55.69 | |
| BioMatrix-4BModel Scale=4B, Molecule Representation=SELFIES2026.06 | 97.34 | 64.95 | 97.76 | 65.46 | 81.7 | 55.04 | |
| BioMatrix-1.7BModel Scale=1.7B, Molecule Representation=SELFIES2026.06 | 96.6 | 64.83 | 97.02 | 65.27 | 79.8 | 54.01 | |
| Llama3.1-8BModel Scale=8B, Variant=OpenMolIns-xlarge2026.06 | 88.22 | 58.77 | 69.82 | 46.73 | 86.48 | 58.25 | |
| Claude-3.52026.06 | 79.7 | 56.78 | 69.62 | 49.51 | 53.61 | 37.75 | |
| Gemini-1.5-pro2026.06 | 77.12 | 54.15 | 78.76 | 53.12 | 47.04 | 28.59 | |
| GPT-4-turbo2026.06 | 76.62 | 53.51 | 73.88 | 50.39 | 39.46 | 25.99 | |
| GPT-4o2026.06 | 71.9 | 47.35 | 68.64 | 44.07 | 39.52 | 24.42 |