Single-property molecular optimization on pLogP
99.95Success Rate (SR)SFT-LLM_Mistral
Evaluation results
| Method | Links | |||
|---|---|---|---|---|
| SFT-LLM_MistralBackbone=Mistral, Protocol=SFT2026.04 | 99.95 | 57 | 9.81 | |
| SFT-LLM_LLaMABackbone=LLaMA, Protocol=SFT2026.04 | 99.93 | 57 | 9.02 | |
| DPO-LLM_MistralBackbone=Mistral, Protocol=DPO2026.04 | 99.6 | 51 | 17.43 | |
| DPO-LLM_LLaMABackbone=LLaMA, Protocol=DPO2026.04 | 99.47 | 48 | 18.1 | |
| GPT-4oshots=52026.04 | 64.2 | 64 | 4.07 | |
| Mistralshots=52026.04 | 64 | 70 | 3.27 | |
| LLaMAshots=52026.04 | 62.6 | 18 | 8.93 | |
| Claude-3.5shots=52026.04 | 56.6 | 69 | 2.35 | |
| LlaSmol_Mistral2026.04 | 44.6 | 45 | 3.75 | |
| GPT-4oshots=02026.04 | 43.2 | 72 | 3.2 | |
| Claude-3.5shots=02026.04 | 37.4 | 73 | 1.54 | |
| Mistralshots=02026.04 | 32.2 | 74 | 2.71 | |
| LLaMAshots=02026.04 | 17 | 74 | 2.41 | |
| ChemLLM2026.04 | 14.4 | 78 | 4.93 |