Retrosynthetic route reconstruction on mkt-cnv-160 v2026-05-12-reaction (holdout)
100Tier-0 ValidityAiZynthFinder MCTS
Evaluation results
| Method | Links | ||||||
|---|---|---|---|---|---|---|---|
| AiZynthFinder MCTSMCTS iterations=100, Maximum search depth=6, Training split=v2026-05-12-reaction2026.06 | 100 | 92.5 | 19.4 | 35 | 28.1 | 10.9 | |
| Ariadne 12LCheckpoint size=20B-token, Training split=v2026-05-12-reaction2026.06 | 100 | 74.4 | 15.6 | 31.9 | 25 | 10.1 | |
| Ariadne 24LCheckpoint size=14B-token, Training split=v2026-05-12-reaction2026.06 | 100 | 81.2 | 22.5 | 42.5 | 35 | 19.4 | |
| Ariadne 24LGeneration prompt / setting=T2026.06 | 100 | 76.9 | 23.8 | 42.5 | 35 | 19.4 | |
| Ariadne 24LGeneration prompt / setting=TL2026.06 | 100 | 90.6 | 26.9 | 46.2 | 38.8 | 19.3 |