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Question Answering on PubMedQA (test)

82.4AccuracyAccurateRAG
55.56862.53469.576.466Jul 17, 2022Mar 2, 2023Oct 17, 2023Jun 2, 2024Jan 16, 2025Sep 2, 2025Apr 19, 2026

Evaluation results

MethodLinks
AccurateRAGLLM Backbone=Llama-3-8B, Fine-tuning=true2025.1082.4———————
Med-PaLM 2Prompting strategy=best2023.0581.8———————
DEEPMED-14B-RLModel Group=DeepResearch Models, Training Stage=RL2026.0181.8———————
GPT-4Date=20232022.0781.2———————
Med-PaLM 2Study=Singhal et al. [6]2025.1281———————
GPT-4Model=GPT-4, Setting=Few-Shot2025.1281———————
AlphaMed-70BModel Group=Medical Reasoning Models2026.0180.9———————
HuatuoGPT-o1-70BModel Group=Medical Reasoning Models2026.0180.6———————
GPT-4-baseFew-shot evaluation protocol=5-shot2023.0580.4———————
DEEPMED-14B-SFTModel Group=DeepResearch Models, Training Stage=SFT2026.0180.4———————
BaiChuan-M2-32BModel Group=Medical Reasoning Models2026.0179.2———————
Flan-PaLMPrompting strategy=best2023.0579———————
QuarkMed-32BModel Group=Medical Reasoning Models2026.0179———————
PubMed ReasonerBackbone Model=GPT2026.0378.32———————
Codex 5-shot CoTDate=2022, Few-shot shots=5, Chain-of-Thought (CoT)=true, Ensemble samples (k)=1002022.0778.2———————
BioGPTDate=2022, Evaluation Protocol=Finetuned SOTA2022.0778.2———————
BioGPTStudy=Luo et al. [8]2025.1278.2———————
GPT-4Model=GPT-4, Setting=Zero-Shot2025.1278.2———————
Human (expert score)2022.0778———————
Human performanceRetrieval/Agent Strategy=Without retrieval2026.0378———————
MeissaFramework=Framework III, Inference Mode=Agent-based, Agent System=MDAgents2026.0377.9———————
M1-1K-32BModel Group=Medical Reasoning Models2026.0177.6———————
MedResaon-8BModel Group=Medical Reasoning Models2026.0177.6———————
M1-1K-7BModel Group=Medical Reasoning Models2026.0177.5———————
MedPalm v2Date=20232022.0777.4———————
PubMed ReasonerBackbone Model=Gemini2026.0377.26———————
Self-reflectionBackbone Model=GPT2026.0377.12———————
Self-reflectionBackbone Model=Gemini2026.0377.08———————
Qwen3-VL-4BFramework=Framework III, Inference Mode=Direct Inference, Training Protocol=SFT2026.0376.8———————
Kimi-K2-Thinking-1TBModel Group=Awesome General Models2026.0176.6———————
PubMed ReasonerBackbone=Qwen2.5-72B2026.0376.42———————
Self-reflection agentBackbone=Qwen2.5-72B2026.0376.22———————
Tongyi-DeepResearch-30BA3BModel Group=DeepResearch Models2026.0176.2———————
Gemini2.5-ProModel Group=Awesome General Models2026.0176———————
Qwen3-30BA3B-ThinkingModel Group=Awesome General Models2026.0176———————
Deepseek-v3.2-685BModel Group=Awesome General Models2026.0175.8———————
Gemini-2.5 ProRetrieval/Agent Strategy=Without retrieval2026.0375.64———————
Llama 3.1 8B InstructModel=Llama 3.1, Parameters=8B, Type=Instruct2026.0475.6——54.06————
Qwen3-14BModel Group=Awesome General Models2026.0175.4———————
GPT-4Few-shot evaluation protocol=5-shot2023.0575.2———————
GPT4oRetrieval/Agent Strategy=Without retrieval, Source=leaderboard2026.0375.2———————
Med-PaLM 2Prompting strategy=Ensemble Refinement (ER)2023.0575———————
GPT-4VFramework=Framework III, Inference Mode=Agent-based, Agent System=MDAgents2026.0375———————
Without retrievalBackbone=Qwen2.5-72B2026.0374.89———————
AccurateRAGLLM Backbone=Llama-2-7B, Fine-tuning=true2025.1074.6———————
DRAGONBackbone=BioLinkBERT-Large2022.1073.4———————
RAFTLLM Backbone=Llama-2-7B, Fine-tuning=true, Chain-of-Thought (CoT)=GPT-4 CoT2025.1073.3———————
RAG methodBackbone Model=GPT2026.0373.28———————
GPT-3.5 Turbo 1106shot=3-shot2024.0272.66———————
BioLinkBERT + GreaseLMBackbone=BioLinkBERT-Large, KG Module=GreaseLM2022.1072.4———————
RAG methodBackbone Model=Gemini2026.0372.3———————
BioLinkBERTBackbone=BioLinkBERT-Large2022.1072.2———————
Mistral 7B Instructshot=3-shot2024.0272.2———————
BioLinkBERT + QAGNNBackbone=BioLinkBERT-Large, KG Module=QAGNN2022.1072.1———————
Gemini-3-flashFramework=Framework III, Inference Mode=Agent-based, Agent System=MDAgents2026.0371.9———————
LLaMA 2 + RAGStudy=This Work, Model size=13B, Setting=Fine-Tuned + RAG2025.1271.8———————
LLaMA 2 + RAGModel=LLaMA 2, Setting=Fine-Tuned + RAG2025.1271.8———————
OracleModel Size=Large, Expertise Distribution=Dist. 32026.0471.25———————
OracleModel Size=Large, Noise Type=Uniform2026.0471.25———————
Self-reflection agentBackbone=Qwen2.5-7B2026.0371.12———————
PubMed ReasonerBackbone=Qwen2.5-7B2026.0371.08———————
Without retrievalBackbone=Qwen2.5-7B2026.0370.2———————
BioMistral 7B DAREshot=3-shot2024.0270———————
Falcon + RAGModel=Falcon, Setting=Fine-Tuned + RAG2025.1268.9———————
RAFTLLM Backbone=Llama-2-7B, Fine-tuning=true, Chain-of-Thought (CoT)=false2025.1068.3———————
BioMistral 7B SLERPshot=3-shot2024.0268.1———————
BioBERTStudy=Jin et al. [17]2025.1268.1———————
Without retrievalBackbone=Qwen2.5-1.5B2026.0368.08———————
BioBERT2026.0468.08——52.72————
Self-reflection agentBackbone=Qwen2.5-1.5B2026.0368.06———————
BioMistral 7B Ensembleshot=3-shot2024.0268———————
LoRA FT 2ep 10k contextFine-Tuning=LoRA, Epochs=2, Context Length=10k2026.0468——46.69————
PubMed ReasonerBackbone=Qwen2.5-1.5B2026.0367.24———————
Gemini-3-flashFramework=Framework III, Inference Mode=Direct Inference2026.0366.7———————
RankRAGLLM Backbone=Llama-3-8B, Fine-tuning=true2025.1065———————
LLaMA 2Model=LLaMA 2, Setting=Fine-Tuned2025.1264.3———————
SFT2026.0364.2———————
NOISYModel Size=Large, Noise Type=Systematic, Expertise Distribution=Dist. 32026.0464.05———————
PPO2026.0363.6———————
Full FT 5ep 16k contextFine-Tuning=Full, Epochs=5, Context Length=16k2026.0462.8——38.69————
Llama 3.2 3B InstructModel=Llama 3.2, Parameters=3B, Type=Instruct2026.0462.4——40.93————
TEPiterations (free phase)=20, iterations (nudged phase)=402026.0162.02———————
GPT-4VFramework=Framework III, Inference Mode=Direct Inference2026.0361.5———————
FalconModel=Falcon, Setting=Fine-Tuned2025.1261.2———————
OracleModel Size=Base, Expertise Distribution=Dist. 32026.0461———————
OracleModel Size=Base, Noise Type=Uniform2026.0461———————
REALMModel Size=Large, Noise Type=Systematic, Expertise Distribution=Dist. 32026.0460.95———————
REALMModel Size=Large, Expertise Distribution=Dist. 2, Noise Type=Uniform2026.0460.55———————
DSPy2026.0160.26———————
BioBERT2022.1060.2———————
HBC2026.0158.8———————
BioMedGPT-LM-7Bshot=3-shot2024.0258.6———————
NOISYModel Size=Base, Noise Type=Systematic, Expertise Distribution=Dist. 32026.0458.45———————
OracleModel Size=Small, Expertise Distribution=Dist. 32026.0458———————
OracleModel Size=Small, Noise Type=Uniform2026.0458———————
REALMModel Size=Large, Expertise Distribution=Dist. 1, Noise Type=Uniform2026.0457.65———————
CoT2026.0157.34———————
Qwen3-VL-4BFramework=Framework III, Inference Mode=Agent-based, Agent System=MDAgents2026.0357.3———————
TextGradsummarization=false2026.0156.96———————
RAAT + DTABase Model=Llama-2-7B, Alignment=Divide-Then-Align2025.0556.659.156.257.652.157.554.5—