Protein Structure Generation on Foldseek AFDB clusters DFS (test)
97.6DesignabilityProteína M_FS^small + Quotient-space diffusion
Evaluation results
| Method | Links | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Proteína M_FS^small + Quotient-space diffusionSampling strategy=SDE, gamma=0.35, Diffusion scheme=Quotient-space2026.04 | 97.6 | 274.7 | 277.1 | 2.24 | 6.69 | 20.99 | 1.68 | 1.55 | |
| FoldFlow (OT)Settings=Representative References2026.04 | 97.2 | 431.4 | 414.1 | 1.35 | 3.1 | 13.62 | 2.9 | 2.32 | |
| FoldFlow (stoc.)Settings=Representative References2026.04 | 97 | 543.6 | 520.4 | 1.21 | 2.09 | 11.59 | 3.69 | 2.71 | |
| FoldFlow (base)Settings=Representative References2026.04 | 96.6 | 601.5 | 566.2 | 1.06 | 1.79 | 9.72 | 3.18 | 3.1 | |
| Proteína M_FS^smallSampling strategy=SDE, gamma=0.352026.04 | 96 | 386.5 | 378.2 | 1.77 | 4.97 | 17.78 | 2.17 | 1.73 | |
| Genie2Settings=Representative References2026.04 | 95.2 | 350 | 313.8 | 1.55 | 3.66 | 11.65 | 2.21 | 1.7 | |
| RFDiffusionSettings=Representative References2026.04 | 94.4 | 253.7 | 252.4 | 2.25 | 5.06 | 19.83 | 1.21 | 1.13 | |
| ProteusSettings=Representative References2026.04 | 94.2 | 225.7 | 226.2 | 2.26 | 5.46 | 16.22 | 1.41 | 1.37 | |
| Proteína M_FS^small + Quotient-space diffusionSampling strategy=SDE, gamma=0.45, Diffusion scheme=Quotient-space2026.04 | 92.6 | 244.5 | 246.3 | 2.24 | 6.68 | 23.47 | 1.43 | 1.28 | |
| Proteína M_FS^smallSampling strategy=SDE, gamma=0.452026.04 | 92.2 | 332.9 | 320.4 | 1.83 | 5.01 | 20.22 | 1.93 | 1.49 | |
| Proteína M_FS^small + Quotient-space diffusionSampling strategy=SDE, gamma=0.50, Diffusion scheme=Quotient-space2026.04 | 90.2 | 228 | 228.7 | 2.25 | 6.59 | 25.24 | 1.32 | 1.17 | |
| Proteína M_FS^smallSampling strategy=SDE, gamma=0.502026.04 | 89.2 | 306.2 | 290.8 | 1.86 | 4.92 | 21.15 | 1.81 | 1.36 | |
| FrameFlowSettings=Representative References2026.04 | 88.6 | 129.9 | 159.9 | 2.52 | 5.88 | 27 | 0.68 | 0.91 | |
| ChromaSettings=Representative References2026.04 | 74.8 | 189 | 184.1 | 2.34 | 4.95 | 18.15 | 1 | 1.08 | |
| FrameDiffSettings=Representative References2026.04 | 65.4 | 194.2 | 258.1 | 2.46 | 5.78 | 23.35 | 1.04 | 1.42 | |
| ESM3Settings=Representative References2026.04 | 22 | 933.9 | 855.4 | 3.19 | 6.71 | 17.73 | 1.53 | 0.98 | |
| Proteína M_FSSampling strategy=ODE, Parameters=200M2026.04 | 19.6 | 85.4 | 21.4 | 2.51 | 5.65 | 27.35 | 0.59 | 0.09 | |
| Proteína M_FS^small + Quotient-space diffusionSampling strategy=ODE, Diffusion scheme=Quotient-space2026.04 | 15.6 | 69.9 | 17.6 | 2.57 | 6.4 | 32.14 | 0.41 | 0.11 | |
| Proteína M_FS^smallSampling strategy=ODE, Parameters=60M2026.04 | 13.8 | 83.2 | 21.9 | 2.45 | 5.63 | 31.76 | 0.58 | 0.12 | |
| Proteína M_FS^small + AF3 alignmentSampling strategy=ODE, Alignment strategy=AF3 alignment2026.04 | 3.8 | 229 | 82.4 | 2.18 | 4.3 | 14.28 | 1.35 | 0.36 |