Protein Sequence Generation on Protein sequences lengths 200-800
86.43pLDDTJoint policy (ours)
Evaluation results
| Method | Links | ||||||
|---|---|---|---|---|---|---|---|
| Joint policy (ours)Model scale=150M-scale, Folding method=ESMFold, Generated sequences=100 per length (200-800)2026.05 | 86.43 | 0.76 | 9.68 | 54.14 | 4.12 | 93.06 | |
| DLM-150M + PAPLModel scale=150M-scale, Folding method=ESMFold, Generated sequences=100 per length (200-800)2026.05 | 81.48 | 0.72 | 8.97 | 59.4 | 3.12 | 91.73 | |
| DLM-150MModel scale=150M-scale, Folding method=ESMFold, Generated sequences=100 per length (200-800)2026.05 | 81.32 | 0.65 | 12 | 42.43 | 3.21 | 92.45 | |
| DPLM-150MModel scale=150M-scale, Folding method=ESMFold, Generated sequences=100 per length (200-800)2026.05 | 80.23 | 0.65 | 12.07 | 48.14 | 3.14 | 92.8 | |
| DPLM-650MModel scale=Large, Folding method=ESMFold, Generated sequences=100 per length (200-800)2026.05 | 79.53 | 0.66 | 11.85 | 49.14 | 3.18 | 92.22 | |
| ProGen2-mediumModel scale=Large, Folding method=ESMFold, Generated sequences=100 per length (200-800)2026.05 | 57.94 | 0.38 | 20.81 | 12.75 | 2.91 | 91.45 | |
| ProGen2-largeModel scale=Large, Folding method=ESMFold, Generated sequences=100 per length (200-800)2026.05 | 55.07 | 0.35 | 22 | 11.87 | 2.73 | 91.48 | |
| ProGen2-smallModel scale=150M-scale, Folding method=ESMFold, Generated sequences=100 per length (200-800)2026.05 | 49.38 | 0.28 | 23.38 | 4.48 | 2.55 | 89.31 | |
| ESM3Model scale=Large, Folding method=ESMFold, Generated sequences=100 per length (200-800)2026.05 | 34.13 | 0.23 | 24.65 | 1.5 | 3.99 | 93.44 | |
| EvoDiffModel scale=150M-scale, Folding method=ESMFold, Generated sequences=100 per length (200-800)2026.05 | 31.84 | 0.21 | 24.76 | 0.43 | 4.05 | 93.19 |