Protein Pocket Design on PDBBind RNA (test)
44.69AARRFDiffusionAA
Evaluation results
| Method | Links | |||
|---|---|---|---|---|
| RFDiffusionAACheckpoint=[1]2024.09 | 44.69 | 0.65 | -0.45 | |
| PocketFlowAffinity Guidance=true, Interaction Geometry Guidance=true, Interaction Learning=true2024.09 | 44.34 | 0.69 | -0.78 | |
| PocketFlow (w/o Aff Guide)Affinity Guidance=false, Interaction Geometry Guidance=true, Interaction Learning=true2024.09 | 42.15 | 0.68 | -0.35 | |
| PocketFlow (w/o Geo Guide)Affinity Guidance=true, Interaction Geometry Guidance=false, Interaction Learning=true2024.09 | 41.73 | 0.77 | -0.65 | |
| PocketFlow (w/o Geo & Aff Guide)Affinity Guidance=false, Interaction Geometry Guidance=false, Interaction Learning=true2024.09 | 39.7 | 0.78 | -0.26 | |
| PocketFlow (w/o Inter Learning)Affinity Guidance=true, Interaction Geometry Guidance=false, Interaction Learning=false2024.09 | 36.27 | 0.82 | -0.23 | |
| dyMEANPre-training=protein-small molecule datasets2024.09 | 25.9 | 0.71 | -0.18 | |
| FAIRPre-training=protein-small molecule datasets2024.09 | 24.9 | 0.8 | 0.13 |