Protein Fitness Prediction on ProteinGym (test) benchmark leaderboard · SOTA2 Research

Protein Fitness Prediction on ProteinGym (test)

0.5087Avg. Spearman CorrelationProSST (K=2048) + ProteinTTT

Evaluation Results

Method	Links
ProSST (K=2048) + ProteinTTT2024.11		0.5087	0.4822	0.447	0.5321	0.4315	0.6507
ProSST (K=2048)2024.11		0.5068	0.4758	0.4448	0.5302	0.4306	0.6526
SaProt (650M) + ProteinTTT2024.11		0.4583	0.4593	0.379	0.4883	0.3754	0.5896
SaProt (650M)2024.11		0.4569	0.4584	0.3785	0.4884	0.367	0.5919
ESM2 (650M) + ProteinTTT2024.11		0.4153	0.4323	0.3376	0.4168	0.3702	0.5195
ESM2 (650M)2024.11		0.4139	0.4254	0.3366	0.4151	0.3691	0.5233
SaProt (35M) + ProteinTTT2024.11		0.4106	0.3783	0.3569	0.443	0.2955	0.5795
SaProt (35M)2024.11		0.4062	0.3721	0.3568	0.439	0.2879	0.5749
ProGen2-large (2.7B) + ProteinTTT2024.11		0.3817	0.4091	0.3113	0.4227	0.3661	0.3993
ProGen2-large (2.7B)2024.11		0.3724	0.4001	0.282	0.4184	0.3711	0.3904
ProGen2-small (151M) + ProteinTTT2024.11		0.3591	0.3827	0.296	0.3875	0.3302	0.3992
ESM2 (35M) + ProteinTTT2024.11		0.3407	0.3407	0.2942	0.355	0.2403	0.4733
ProGen2-small (151M)2024.11		0.3255	0.3316	0.2681	0.373	0.3283	0.3264
ESM2 (35M)2024.11		0.3211	0.3137	0.2907	0.3435	0.2184	0.4392