Peptide SMILES Generation benchmark leaderboard · SOTA2 Research

Peptide SMILES Generation

98.7Validity ScoreSFT-RL

Evaluation Results

Method	Links
SFT-RL2025.08		98.7	99.8	23.8	83.3	9.84	95.6
SFT-RL2025.08		98	99.9	51	83	4.12	93.7
CoT-SFT2025.08		95.6	99.9	95.4	19.6	8.82	87.9
CoT-SFT2025.08		95.3	99.9	98.9	19.7	1.85	67.1
GPT-4o2025.08		92.6	99.6	74.6	2.3	0.17	7
PepThink-R12025.08		90	100	56	89	4.42	96
PepThink-R12025.08		90	100	30	89	11.81	98.4
Random mutation2025.08		87.6	99.8	99.1	0.3	0.61	20.8
GPT-4o2025.08		84	98.4	93.7	4.3	0.35	19.8
GPT-52025.08		82.1	99.6	95.9	10.7	0.85	38.6
DeepSeek-R1-Llama-8B2025.08		67.9	87.5	42.8	4.1	0.12	7.9
DeepSeek-R1-Llama-8B2025.08		55.7	83.9	55.5	3.3	0.12	7.2
Qwen3-30B-thinking2025.08		37.4	95.4	36.8	5.2	0.04	3.2
Qwen3-30B-thinking2025.08		34.6	98.9	39	1.5	0.02	1.8