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Non-germline residue prediction on OAS held-out germlines (test)

53.8Non-germline AccuracyNearest neighbor upper-bound
11.05622.15333.2544.347May 7, 2026

Evaluation results

MethodLinks
Nearest neighbor upper-boundAdditional input information=True2026.0553.8
MochiDiff germlineModel type=Germline absorbing state model, Additional input information=True2026.0546.3
MochiDiff uniformModel type=Uniform diffusion model2026.0526.1
IgLMType=Autoregressive antibody-specific pLM2026.0525.7
MochiDiff absorbingModel type=MASK absorbing state model2026.0525.5
ESM-2 finetuned (MLM)Training protocol=Finetuned on antibody specific training set, Loss function=Masked Language Modeling (MLM)2026.0524.7
AbLang-2Training dataset=OAS, Loss function=Focal loss2026.0522.9
ESM-2Model size=650M2026.0519.3
Nearest neighbor baseline2026.0512.7