ResearchBenchmarksEnzyme-Substrate Interaction Prediction on E. coli screening dataset case studyEnzyme-Substrate Interaction Prediction on E. coli screening dataset case studyFollow6Hits@10RAMMESI-0.241.3834.62Jun 22, 2026Evaluation resultsMethodMethodLinksHits@10Hits@100Enrichment Factor (EF) @ 1.0%RAMMESI2026.066167.12ESP2026.06354.27OmniESI2026.06394.62RandomForest2026.06251.78LightGBM2026.06021.42DNN2026.06022.49ProSmith2026.06043.2VIPER2026.06011.07FusionESP2026.06031.91