De Novo Design on 10 de novo shared-core domains
76Success RateOpus 4.6
Evaluation Results
| Method | Links | |
|---|---|---|
| Opus 4.6Turns=202026.03 | 76 | |
| Sonnet 4.6Turns=202026.03 | 71.5 | |
| Sonnet 4.5Turns=202026.03 | 69.5 | |
| GPT-5.2Turns=202026.03 | 67 | |
| Sonnet 4.5Turns=52026.03 | 66.5 | |
| Sonnet 4.6Turns=52026.03 | 66.5 | |
| Opus 4.6Turns=52026.03 | 65.5 | |
| GPT-5.2Turns=52026.03 | 62.5 | |
| Gemini 3.1 ProTurns=202026.03 | 60.5 | |
| Gemini 2.0 FlashTurns=202026.03 | 60.5 | |
| Gemini 3.1 ProTurns=52026.03 | 57.3 | |
| GPT-4oTurns=202026.03 | 55 | |
| GPT-4oTurns=52026.03 | 53 | |
| Gemini 2.0 FlashTurns=52026.03 | 43.2 | |
| Sonnet 4.5Turns=12026.03 | 29 | |
| GPT-5.2Turns=12026.03 | 25.6 | |
| Gemini 3.1 ProTurns=12026.03 | 24 | |
| Opus 4.6Turns=12026.03 | 23.8 | |
| Sonnet 4.6Turns=12026.03 | 22.9 | |
| Gemini 2.0 FlashTurns=12026.03 | 19.5 | |
| GPT-4oTurns=12026.03 | 12.8 |