Binding affinity prediction on SKEMPI v2.0
0.28Spearman ρRedNet
Evaluation Results
| Method | Links | |||
|---|---|---|---|---|
| RedNetσ=0.02, scoring_method=cd_ll_ref2026.05 | 0.28 | 0.2 | 78 | |
| ProteinMPNNσ=0.02, scoring_method=ref2026.05 | 0.26 | 0.18 | 80 | |
| RedNetσ=0, scoring_method=cd_ll_ref2026.05 | 0.26 | 0.18 | 78 | |
| RedNetσ=0.02, scoring_method=global2026.05 | 0.26 | 0.19 | 80 | |
| RedNetσ=0.02, scoring_method=cd_ll2026.05 | 0.26 | 0.19 | 79 | |
| ESM-IFσ=0, scoring_method=global2026.05 | 0.24 | 0.18 | 79 | |
| ProteinMPNNσ=0.02, scoring_method=cd_ll_ref2026.05 | 0.24 | 0.18 | 78 | |
| RedNetσ=0.02, scoring_method=ref2026.05 | 0.24 | 0.18 | 81 | |
| ProteinMPNNσ=0.02, scoring_method=mt2026.05 | 0.23 | 0.17 | 80 | |
| RedNetσ=0, scoring_method=global2026.05 | 0.23 | 0.17 | 80 | |
| RedNetσ=0, scoring_method=cd_ll2026.05 | 0.23 | 0.17 | 78 | |
| RedNetσ=0, scoring_method=ref2026.05 | 0.22 | 0.16 | 80 | |
| RedNetσ=0.02, scoring_method=mt2026.05 | 0.22 | 0.16 | 81 | |
| RedNetσ=0, scoring_method=mt2026.05 | 0.21 | 0.15 | 80 | |
| RedNetσ=0.02, scoring_method=ll2026.05 | 0.21 | 0.15 | 79 | |
| ESM-IFσ=0, scoring_method=mt2026.05 | 0.2 | 0.14 | 79 | |
| ESM-IFσ=0, scoring_method=ref2026.05 | 0.2 | 0.14 | 78 | |
| RedNetσ=0, scoring_method=ll2026.05 | 0.18 | 0.13 | 79 | |
| PiFoldσ=0, scoring_method=ll2026.05 | 0.17 | 0.13 | 78 | |
| ProteinMPNNσ=0.02, scoring_method=ll2026.05 | 0.17 | 0.12 | 78 | |
| ProteinMPNNσ=0.02, scoring_method=global2026.05 | 0.17 | 0.12 | 78 | |
| ESM-IFσ=0, scoring_method=ll2026.05 | 0.16 | 0.12 | 77 | |
| ESM-IFσ=0, scoring_method=cd_ll2026.05 | 0.15 | 0.15 | 77 | |
| ESM-IFσ=0, scoring_method=cd_ll_ref2026.05 | 0.15 | 0.1 | 77 | |
| PiFoldσ=0, scoring_method=cd_ll2026.05 | 0.15 | 0.11 | 75 | |
| ProteinMPNNσ=0.02, scoring_method=cd_ll2026.05 | 0.1 | 0.07 | 76 | |
| PiFoldσ=0, scoring_method=cd_ll_ref2026.05 | 0 | 0 | 71 | |
| PiFoldσ=0, scoring_method=mt2026.05 | -0.03 | -0.02 | 72 | |
| PiFoldσ=0, scoring_method=ref2026.05 | -0.12 | -0.09 | 69 | |
| PiFoldσ=0, scoring_method=global2026.05 | -0.17 | -0.13 | 67 |