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Binary Protein-Protein Interaction Prediction on SHS27k Binding (BFS)

67.23Micro-F1Saprot+
48.322853.231458.1463.0486May 11, 2026

Evaluation results

MethodLinks
Saprot+L3-PPI framework=integrated2026.0567.23
GNN-PPI+L3-PPI framework=integrated2026.0567.01
ESM2-650M+L3-PPI framework=integrated2026.0565.09
MLP+L3-PPI framework=integrated2026.0563.7
GearNet+L3-PPI framework=integrated2026.0559.6
GNN-PPIL3-PPI framework=excluded2026.0558.04
DPPI+L3-PPI framework=integrated2026.0557.01
MLPL3-PPI framework=excluded2026.0556.77
ProstT5+L3-PPI framework=integrated2026.0556.31
DPPIL3-PPI framework=excluded2026.0555.72
PIPR+L3-PPI framework=integrated2026.0554.3
PIPRL3-PPI framework=excluded2026.0552.42
DNN-PPI+L3-PPI framework=integrated2026.0551.71
DNN-PPIL3-PPI framework=excluded2026.0549.05