Substrate AI, Inc.
AI agents for healthcare revenue cycle management that autonomously complete claim status, appeals, policy reviews, refunds, and payment posting tasks.
Where Substrate AI, Inc. ranks
Current edition · updated Oct 20, 2026- Ranked #4Verify documentsHealthcare and life sciences · Payer Policy Review · 10 products reviewed
- Ranked #7Verify insurance coverageHealthcare and life sciences · Eligibility Agent · 14 products reviewed
- Ranked #10Update business systemsHealthcare and life sciences · Exception Posting · 15 products reviewed
About Substrate AI, Inc.
Substrate's AI agents automate the click-work & data entry in revenue cycle management. Our agents perform repetitive and time-consuming tasks on behalf of medical billers, significantly increasing efficiency and reducing errors.
Products
Combines 276/277 messages, browser agents, and direct payer APIs into a single unified response for claim status checking.
Detects claims pended or denied for medical records, then retrieves, validates, and submits them to payers to recover trapped appeal dollars.
Automatically posts exceptions including case rates, globals, payer recoups, and more.
Validates credit balances, checks for offsetting claims, and processes refunds within limits.
AI agent for front-end denials and eligibility verification.
Verifies patient eligibility for claim routing, COB, and eligibility denials in real-time.
Models and validates medical records against specific coverage criteria.
Classifies and extracts data from any medical document automatically.
What customers say
- Claim Status Agent
Heading Health uses Substrate's Claim Status Agent to replace manual payer-portal checks and automate AR follow-up. Substrate reports more than 100 hours saved monthly and 70% of no-response claims statused without human…
Case study - Claim Status Agent
NextGen RCM Services uses Substrate's Claim Status Agent to automate claim ingestion, payer status retrieval and worklist updates across practice clients. Substrate reports fourfold biller efficiency, 75% lower…
Case study - Appeals Agent
Heading Health uses Substrate's Appeals Agent to retrieve medical records, submit appeals and track adjudication, alongside Claim Status Agent monitoring. Substrate reports 88% of appeals submitted handsfree, over 40% of…
Case study
Security and compliance
As reported by Substrate AI, Inc.. Ask for audit reports before you buy.
- SOC 2Compliant
- HIPAACompliant
- End-to-end encryption for data in transit and at rest
- Zero-trust architecture
- Periodic security audits and compliance checks
- Granular access controls
Is this your company?
Claim the profile to keep facts current, answer buyers and submit evidence for the next ranking review.
Claim Substrate AI, Inc.