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SigProfilerExtractor
SigProfilerExtractor is an open-source tool hosted under the SigProfilerSuite GitHub organization for de novo extraction of mutational signatures from cancer samples.
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Latest updates from SigProfilerExtractor
New feature
Claude Opus 5 integrated into GitHub Copilot
GitHub has integrated Anthropic's Claude Opus 5 model into GitHub Copilot. The model is optimized for complex, autonomous coding tasks, including regression verification and multi-step execution. It is available to users on Copilot Pro+, Max, Business, and Enterprise plans across various environments, including Visual Studio Code, JetBrains, and mobile applications. Access requires administrator enablement for enterprise and business plans.
MentionedAnthropic
New feature
GitHub Mobile adds Copilot fix workflow for CI failures
GitHub Mobile now includes a feature allowing users to address failed GitHub Actions checks using the Copilot coding agent. When a check fails, users can select 'Fix with Copilot' from the mobile interface, prompting the agent to analyze the failure, create a new pull request with a potential fix, and request a review. This workflow is available on the latest production builds for iOS and Android.
New feature
GitHub MCP Server updated for upcoming stateless specification
The GitHub MCP (Model Context Protocol) Server has been updated to support the upcoming stateless MCP specification ahead of its July 28, 2026 release. Improvements include a more scalable architecture through the removal of Redis sessions, optimized payload handling to avoid deep packet inspection, and an upgraded implementation for elicitation. This update maintains backwards compatibility with existing SDKs while enabling faster, more efficient agentic connections.
MentionedGo
New featurePartnership
GitHub Copilot cloud agent for Linear released
GitHub has released a generally available Copilot cloud agent integration for Linear. This tool allows users to assign issues directly to the Copilot agent, which can analyze contents, create draft pull requests, execute via GitHub Actions, and provide progress updates within the Linear interface. The integration supports custom agent configurations, model selection, and branch management, and is available to Copilot Pro, Pro+, Business, and Enterprise subscribers.
PartnerLinear