An optimised re-implementation of the index, call-methylation and eventalign modules in Nanopolish. Given a set of basecalled Nanopore reads and the raw signals, f5c call-methylation detects the methylated cytosine and f5c eventalign aligns raw nanopore signals (events) to the reference k-mers.
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Anthropic’s Claude Opus 5 model is now available within GitHub Copilot. The model is designed for complex, agentic coding tasks requiring extensive reasoning and multi-step tool execution. It features enhanced safeguards for high-harm cyber content. The model is accessible to Copilot Pro+, Max, Business, and Enterprise users across various GitHub Copilot interfaces, including Visual Studio Code, the Copilot CLI, and the GitHub mobile application.
GitHub has introduced a new feature for the GitHub Mobile application on iOS and Android that allows users to address failed CI/CD checks using the Copilot coding agent. When a GitHub Actions check fails on a pull request, users can select 'Fix with Copilot' to trigger an investigation and automated fix attempt. The agent creates a new pull request incorporating the repair, which is then submitted for review, streamlining the process of handling CI/CD issues remotely.
The Copilot cloud agent for Linear is now generally available, allowing users to assign Linear issues to an asynchronous, autonomous background agent. The agent analyzes issue contents, creates draft pull requests, and provides status updates directly within the Linear activity timeline. The integration offers configurable features such as model selection, support for custom repository-specific agents, and branch management. It is accessible to users with GitHub Copilot Pro, Pro+, Business, and Enterprise subscriptions.