Clair3 is a germline small variant caller for long reads developed by HKU-BAL. It combines pileup calling and full-alignment approaches for high-performance long-read variant calling.
Clair3 is a germline small variant caller for long reads developed by HKU-BAL. It combines pileup calling and full-alignment approaches for high-performance long-read variant calling.
A germline small variant caller for long reads that symphonizes pileup calling for speed with full-alignment for precision and recall.
What customers say
“GitHub Copilot will bring huge benefits to our engineering teams by reducing the amount of time spent on boilerplate code, keeping the teams in their flow state, allowing them to ship high-quality products to market faster.”
“GitHub's endless plug-ins, beautiful UI, and optimized workflows make devs happy. Happy and empowered engineers write the best code, make better decisions, and have more time to innovate.”
Jen Peck Senior Director of Engineering @ RedfinClair3 customer
“At Uber, we continuously strive to improve our developer experience. We migrated code hosting and review to GitHub and are adopting GitHub Copilot to boost overall developer productivity.”
Ali-Reza Adl-Tabatabai Senior Director of Engineering @ UberClair3 customer
Security and compliance
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Anthropic’s Claude Opus 5 model is now integrated into GitHub Copilot. The model is optimized for complex, multi-step agentic coding tasks, including autonomous code changes and regression verification. It provides enhanced security features for cyber-related content and is available for Copilot Pro+, Max, Business, and Enterprise plans across various GitHub surfaces including Visual Studio Code, JetBrains, and GitHub Mobile.
Copilot Fixes for Failed GitHub Actions Now on Mobile
GitHub Mobile has introduced a one-tap workflow to address failed CI actions. Users can now invoke the Copilot coding agent directly from a failed GitHub Actions check on a pull request. The agent analyzes the failure, proposes a fix by creating a secondary pull request, and notifies the user for review. This feature is available on the latest production builds for both iOS and Android.
Company news
GitHub MCP Server Updated for Stateless Protocol Support
GitHub has updated its MCP (Model Context Protocol) Server to support the upcoming stateless MCP specification, scheduled for release on July 28, 2026. The update introduces performance improvements such as the removal of Redis-based sessions, reduced payload inspection, and an upgraded elicitation implementation for user login. These changes allow for better scalability and faster connection handshakes while maintaining backward compatibility with existing tier 1 SDKs.
New feature
Copilot Cloud Agent Integration with Linear Available
GitHub has launched general availability for the Copilot cloud agent for Linear, enabling users to assign issues directly to the AI agent. The agent analyzes issue contents, creates draft pull requests in ephemeral environments using GitHub Actions, and posts progress updates back to the Linear interface. Users can configure model selection, custom agents, and branch settings directly from their Linear workspace.
