# Virtual Screening on DUD-E (test)

Source: [Virtual Screening on DUD-E (test)](<https://www.sota2.com/research/sota/virtual-screening-on-dud-e-test>)

Collection index: [llms.txt](<https://www.sota2.com/research/llms.txt>)

Data updated: 2026-02-26T05:26:18.734Z

Evaluation of model performance on Virtual Screening using the test split of the DUD-E dataset, measured using metrics like AUROC, BEDROC, and Enrichment Factors (EF).

A research result applies to its stated dataset, split, metric and evaluation configuration. Compare like-for-like settings, preserve the metric's unit and direction, and distinguish paper-reported results from independent reproduction. The best result recorded here is not a claim of exhaustive, current global coverage.

| Scope | Recorded value |
| --- | --- |
| Task | Virtual Screening |
| Dataset (including any stated split) | DUD-E (test) |
| Metric | AUROC |
| Unit | PERCENT |
| Direction | Higher is better |
| Results loaded | 6 of 6 |
| Coverage | All results currently returned for this benchmark |

Evaluation settings may differ between results. The original papers and recorded configurations are needed to establish comparability. A shared metric name alone does not establish an identical protocol.

## Metrics

- [AUROC](<https://www.sota2.com/research/sota/virtual-screening-on-dud-e-test.md?metric=AUROC>): Higher is better; unit: PERCENT.

- [BEDROC](<https://www.sota2.com/research/sota/virtual-screening-on-dud-e-test.md?metric=BEDROC>): Higher is better; unit: SCALAR.

- [EF0.5%](<https://www.sota2.com/research/sota/virtual-screening-on-dud-e-test.md?metric=EF0.5%25>): Higher is better; unit: SCALAR.

- [EF1%](<https://www.sota2.com/research/sota/virtual-screening-on-dud-e-test.md?metric=EF1%25>): Higher is better; unit: SCALAR.

- [EF5%](<https://www.sota2.com/research/sota/virtual-screening-on-dud-e-test.md?metric=EF5%25>): Higher is better; unit: SCALAR.

## Recorded results

| Method | AUROC | Result date | Report paper |
| --- | --- | --- | --- |
| Glide-SP | 76.7 | Not recorded | 6995476f09c33900fcd6d4c4 |
| Vina | 71.6 | Not recorded | 6995476f09c33900fcd6d4c4 |
| Planet | 71.6 | Not recorded | 6995476f09c33900fcd6d4c4 |
| RFscore | 65.21 | Not recorded | 6995476f09c33900fcd6d4c4 |
| Pafnucy | 63.11 | Not recorded | 6995476f09c33900fcd6d4c4 |
| OnionNet | 59.71 | Not recorded | 6995476f09c33900fcd6d4c4 |

### Glide-SP

AUROC: 76.7. Result ID: 699ab2505698665ec43fe655.

[Reporting paper](<https://www.sota2.com/research/paper/6995476f09c33900fcd6d4c4.md>)

Recorded evaluation configuration: {"Method Category":"docking-based"}. This record does not assert independent reproduction.

### Vina

AUROC: 71.6. Result ID: 699ab2505698665ec43fe654.

[Reporting paper](<https://www.sota2.com/research/paper/6995476f09c33900fcd6d4c4.md>)

Recorded evaluation configuration: {"Method Category":"docking-based"}. This record does not assert independent reproduction.

### Planet

AUROC: 71.6. Result ID: 699ab2505698665ec43fe659.

[Reporting paper](<https://www.sota2.com/research/paper/6995476f09c33900fcd6d4c4.md>)

Recorded evaluation configuration: {"Method Category":"learning-based"}. This record does not assert independent reproduction.

### RFscore

AUROC: 65.21. Result ID: 699ab2505698665ec43fe656.

[Reporting paper](<https://www.sota2.com/research/paper/6995476f09c33900fcd6d4c4.md>)

Recorded evaluation configuration: {"Method Category":"learning-based"}. This record does not assert independent reproduction.

### Pafnucy

AUROC: 63.11. Result ID: 699ab2505698665ec43fe657.

[Reporting paper](<https://www.sota2.com/research/paper/6995476f09c33900fcd6d4c4.md>)

Recorded evaluation configuration: {"Method Category":"learning-based"}. This record does not assert independent reproduction.

### OnionNet

AUROC: 59.71. Result ID: 699ab2505698665ec43fe658.

[Reporting paper](<https://www.sota2.com/research/paper/6995476f09c33900fcd6d4c4.md>)

[Method origin paper](<https://www.sota2.com/research/paper/68fa3a9d1e209131ce8cc209.md>)

Recorded evaluation configuration: {"Method Category":"learning-based"}. This record does not assert independent reproduction.

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