# Time point Subspace Disentanglement on Malaria scRNA-seq

Source: [Time point Subspace Disentanglement on Malaria scRNA-seq](<https://www.sota2.com/research/sota/time-point-subspace-disentanglement-on-malaria-scrna-seq>)

Collection index: [llms.txt](<https://www.sota2.com/research/llms.txt>)

Data updated: 2026-02-26T06:04:21.686Z

Evaluation of Time point Subspace Disentanglement performance on the Malaria single-cell RNA sequencing (scRNA-seq) dataset, measured using Silhouette scores for infection and time labels.

A research result applies to its stated dataset, split, metric and evaluation configuration. Compare like-for-like settings, preserve the metric's unit and direction, and distinguish paper-reported results from independent reproduction. The best result recorded here is not a claim of exhaustive, current global coverage.

| Scope | Recorded value |
| --- | --- |
| Task | Time point Subspace Disentanglement |
| Dataset (including any stated split) | Malaria scRNA-seq |
| Metric | Silhouette Score (Infection) |
| Unit | SCALAR |
| Direction | Higher is better |
| Results loaded | 6 of 6 |
| Coverage | All results currently returned for this benchmark |

Evaluation settings may differ between results. The original papers and recorded configurations are needed to establish comparability. A shared metric name alone does not establish an identical protocol.

## Metrics

- [Silhouette Score (Infection)](<https://www.sota2.com/research/sota/time-point-subspace-disentanglement-on-malaria-scrna-seq.md?metric=Silhouette%20Score%20(Infection)>): Higher is better; unit: SCALAR.

- [Silhouette Score (Time)](<https://www.sota2.com/research/sota/time-point-subspace-disentanglement-on-malaria-scrna-seq.md?metric=Silhouette%20Score%20(Time)>): Higher is better; unit: SCALAR.

## Recorded results

| Method | Silhouette Score (Infection) | Result date | Report paper |
| --- | --- | --- | --- |
| PCA | -0.014 | Not recorded | 68fa5f6f1e209131ce9e9d47 |
| VAE | -0.036 | Not recorded | 68fa5f6f1e209131ce9e9d47 |
| hsVAE | -0.069 | Not recorded | 68fa5f6f1e209131ce9e9d47 |
| sPCA | -0.075 | Not recorded | 68fa5f6f1e209131ce9e9d47 |
| supVAE | -0.087 | Not recorded | 68fa5f6f1e209131ce9e9d47 |
| sisPCA | -0.097 | Not recorded | 68fa5f6f1e209131ce9e9d47 |

### PCA

Silhouette Score (Infection): -0.014. Result ID: 698bc7947a967eddb7714c42.

[Reporting paper](<https://www.sota2.com/research/paper/68fa5f6f1e209131ce9e9d47.md>)

Recorded evaluation configuration: {"Linearity":"Linear"}. This record does not assert independent reproduction.

### VAE

Silhouette Score (Infection): -0.036. Result ID: 698bc7947a967eddb7714c45.

[Reporting paper](<https://www.sota2.com/research/paper/68fa5f6f1e209131ce9e9d47.md>)

[Method origin paper](<https://www.sota2.com/research/paper/68fa619a1e209131ce9f5097.md>)

[Implementation](<http://github.com/dpkingma/nips14-ssl>)

Recorded evaluation configuration: {"Linearity":"Non-linear"}. This record does not assert independent reproduction.

### hsVAE

Silhouette Score (Infection): -0.069. Result ID: 698bc7947a967eddb7714c47.

[Reporting paper](<https://www.sota2.com/research/paper/68fa5f6f1e209131ce9e9d47.md>)

[Method origin paper](<https://www.sota2.com/research/paper/68fa5edf1e209131ce9e5ecc.md>)

Recorded evaluation configuration: {"Linearity":"Non-linear"}. This record does not assert independent reproduction.

### sPCA

Silhouette Score (Infection): -0.075. Result ID: 698bc7947a967eddb7714c43.

[Reporting paper](<https://www.sota2.com/research/paper/68fa5f6f1e209131ce9e9d47.md>)

Recorded evaluation configuration: {"Linearity":"Linear"}. This record does not assert independent reproduction.

### supVAE

Silhouette Score (Infection): -0.087. Result ID: 698bc7947a967eddb7714c46.

[Reporting paper](<https://www.sota2.com/research/paper/68fa5f6f1e209131ce9e9d47.md>)

Recorded evaluation configuration: {"Linearity":"Non-linear"}. This record does not assert independent reproduction.

### sisPCA

Silhouette Score (Infection): -0.097. Result ID: 698bc7947a967eddb7714c44.

[Reporting paper](<https://www.sota2.com/research/paper/68fa5f6f1e209131ce9e9d47.md>)

[Method origin paper](<https://www.sota2.com/research/paper/68fa5f6f1e209131ce9e9d47.md>)

[Implementation](<https://github.com/JiayuSuPKU/sispca>)

Recorded evaluation configuration: {"Linearity":"Linear"}. This record does not assert independent reproduction.

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