# Retrosynthesis planning on Pistachio Reachable Source: [Retrosynthesis planning on Pistachio Reachable]() Collection index: [llms.txt]() Data updated: 2026-05-12T10:51:49.934Z Evaluation of models performing retrosynthesis planning on the Pistachio Reachable dataset, measured using Solve Rate (%). A research result applies to its stated dataset, split, metric and evaluation configuration. Compare like-for-like settings, preserve the metric's unit and direction, and distinguish paper-reported results from independent reproduction. The best result recorded here is not a claim of exhaustive, current global coverage. | Scope | Recorded value | | --- | --- | | Task | Retrosynthesis planning | | Dataset (including any stated split) | Pistachio Reachable | | Metric | Solve Rate | | Unit | PERCENT | | Direction | Higher is better | | Results loaded | 30 of 30 | | Coverage | All results currently returned for this benchmark | Evaluation settings may differ between results. The original papers and recorded configurations are needed to establish comparability. A shared metric name alone does not establish an identical protocol. ## Metrics - [Solve Rate](): Higher is better; unit: PERCENT. ## Recorded results | Method | Solve Rate | Result date | Report paper | | --- | --- | --- | --- | | RootAligned | 99.3 | Not recorded | 68fa4a371e209131ce93cac1 | | RootAligned | 99.3 | Not recorded | 68fa4a371e209131ce93cac1 | | RootAligned | 99.3 | Not recorded | 68fa4a371e209131ce93cac1 | | LocalRetro | 99.3 | Not recorded | 68fa4a371e209131ce93cac1 | | LocalRetro | 99.3 | Not recorded | 68fa4a371e209131ce93cac1 | | LLM-Syn-Planner | 99.3 | Not recorded | 68fa4a371e209131ce93cac1 | | LLM-Syn-Planner | 99.3 | Not recorded | 68fa4a371e209131ce93cac1 | | RootAligned | 98.7 | Not recorded | 68fa4a371e209131ce93cac1 | | RootAligned | 98.7 | Not recorded | 68fa4a371e209131ce93cac1 | | RootAligned | 98.7 | Not recorded | 68fa4a371e209131ce93cac1 | | LLM-Syn-Planner | 98 | Not recorded | 68fa4a371e209131ce93cac1 | | LLM-Syn-Planner | 98 | Not recorded | 68fa4a371e209131ce93cac1 | | Graph2Edits | 97.5 | Not recorded | 68fa4a371e209131ce93cac1 | | LocalRetro | 97.3 | Not recorded | 68fa4a371e209131ce93cac1 | | LLM-Syn-Planner | 96.7 | Not recorded | 68fa4a371e209131ce93cac1 | | LocalRetro | 95.3 | Not recorded | 68fa4a371e209131ce93cac1 | | Graph2Edits | 95 | Not recorded | 68fa4a371e209131ce93cac1 | | Graph2Edits | 94.2 | Not recorded | 68fa4a371e209131ce93cac1 | | Graph2Edits | 94 | Not recorded | 68fa4a371e209131ce93cac1 | | LLM-Syn-Planner | 93.3 | Not recorded | 68fa4a371e209131ce93cac1 | | LocalRetro | 90 | Not recorded | 68fa4a371e209131ce93cac1 | | Graph2Edits | 88.4 | Not recorded | 68fa4a371e209131ce93cac1 | | LocalRetro | 86.7 | Not recorded | 68fa4a371e209131ce93cac1 | | Graph2Edits | 77.3 | Not recorded | 68fa4a371e209131ce93cac1 | | LLM | 20.7 | Not recorded | 68fa4a371e209131ce93cac1 | | LLM | 19.3 | Not recorded | 68fa4a371e209131ce93cac1 | | LLM | 17.3 | Not recorded | 68fa4a371e209131ce93cac1 | | LLM | 14.7 | Not recorded | 68fa4a371e209131ce93cac1 | | LLM | 13.3 | Not recorded | 68fa4a371e209131ce93cac1 | | LLM | 12.7 | Not recorded | 68fa4a371e209131ce93cac1 | ### RootAligned Solve Rate: 99.3. Result ID: 6a03063a47f34ce924e69d0b. [Reporting paper]() [Method origin paper]() Recorded evaluation configuration: {"Search Strategy":"MCTS","N":"100"}. This record does not assert independent reproduction. ### RootAligned Solve Rate: 99.3. Result ID: 6a03063a47f34ce924e69d0c. [Reporting paper]() [Method origin paper]() Recorded evaluation configuration: {"Search Strategy":"MCTS","N":"300"}. This record does not assert independent reproduction. ### RootAligned Solve Rate: 99.3. Result ID: 6a03063a47f34ce924e69d0d. [Reporting paper]() [Method origin paper]() Recorded evaluation configuration: {"Search Strategy":"MCTS","N":"500"}. This record does not assert independent reproduction. ### LocalRetro Solve Rate: 99.3. Result ID: 6a03063a47f34ce924e69d18. [Reporting paper]() Recorded evaluation configuration: {"Search Strategy":"Retro\*","N":"300"}. This record does not assert independent reproduction. ### LocalRetro Solve Rate: 99.3. Result ID: 6a03063a47f34ce924e69d19. [Reporting paper]() Recorded evaluation configuration: {"Search Strategy":"Retro\*","N":"500"}. This record does not assert independent reproduction. ### LLM-Syn-Planner Solve Rate: 99.3. Result ID: 6a03063a47f34ce924e69d24. [Reporting paper]() [Method origin paper]() Recorded evaluation configuration: {"Backbone":"DeepSeek-V3","N":"300"}. This record does not assert independent reproduction. ### LLM-Syn-Planner Solve Rate: 99.3. Result ID: 6a03063a47f34ce924e69d25. [Reporting paper]() [Method origin paper]() Recorded evaluation configuration: {"Backbone":"DeepSeek-V3","N":"500"}. This record does not assert independent reproduction. ### RootAligned Solve Rate: 98.7. Result ID: 6a03063a47f34ce924e69d14. [Reporting paper]() [Method origin paper]() Recorded evaluation configuration: {"Search Strategy":"Retro\*","N":"100"}. This record does not assert independent reproduction. ### RootAligned Solve Rate: 98.7. Result ID: 6a03063a47f34ce924e69d15. [Reporting paper]() [Method origin paper]() Recorded evaluation configuration: {"Search Strategy":"Retro\*","N":"300"}. This record does not assert independent reproduction. ### RootAligned Solve Rate: 98.7. Result ID: 6a03063a47f34ce924e69d16. [Reporting paper]() [Method origin paper]() Recorded evaluation configuration: {"Search Strategy":"Retro\*","N":"500"}. This record does not assert independent reproduction. ### LLM-Syn-Planner Solve Rate: 98. Result ID: 6a03063a47f34ce924e69d21. [Reporting paper]() [Method origin paper]() Recorded evaluation configuration: {"Backbone":"GPT-4o","N":"300"}. This record does not assert independent reproduction. ### LLM-Syn-Planner Solve Rate: 98. Result ID: 6a03063a47f34ce924e69d22. [Reporting paper]() [Method origin paper]() Recorded evaluation configuration: {"Backbone":"GPT-4o","N":"500"}. This record does not assert independent reproduction. ### Graph2Edits Solve Rate: 97.5. Result ID: 6a03063a47f34ce924e69d13. [Reporting paper]() Recorded evaluation configuration: {"Search Strategy":"Retro\*","N":"500"}. This record does not assert independent reproduction. ### LocalRetro Solve Rate: 97.3. Result ID: 6a03063a47f34ce924e69d17. [Reporting paper]() Recorded evaluation configuration: {"Search Strategy":"Retro\*","N":"100"}. This record does not assert independent reproduction. ### LLM-Syn-Planner Solve Rate: 96.7. Result ID: 6a03063a47f34ce924e69d23. [Reporting paper]() [Method origin paper]() Recorded evaluation configuration: {"Backbone":"DeepSeek-V3","N":"100"}. This record does not assert independent reproduction. ### LocalRetro Solve Rate: 95.3. Result ID: 6a03063a47f34ce924e69d10. [Reporting paper]() Recorded evaluation configuration: {"Search Strategy":"MCTS","N":"500"}. This record does not assert independent reproduction. ### Graph2Edits Solve Rate: 95. Result ID: 6a03063a47f34ce924e69d12. [Reporting paper]() Recorded evaluation configuration: {"Search Strategy":"Retro\*","N":"300"}. This record does not assert independent reproduction. ### Graph2Edits Solve Rate: 94.2. Result ID: 6a03063a47f34ce924e69d0a. [Reporting paper]() Recorded evaluation configuration: {"Search Strategy":"MCTS","N":"500"}. This record does not assert independent reproduction. ### Graph2Edits Solve Rate: 94. Result ID: 6a03063a47f34ce924e69d11. [Reporting paper]() Recorded evaluation configuration: {"Search Strategy":"Retro\*","N":"100"}. This record does not assert independent reproduction. ### LLM-Syn-Planner Solve Rate: 93.3. Result ID: 6a03063a47f34ce924e69d20. [Reporting paper]() [Method origin paper]() Recorded evaluation configuration: {"Backbone":"GPT-4o","N":"100"}. This record does not assert independent reproduction. ### LocalRetro Solve Rate: 90. Result ID: 6a03063a47f34ce924e69d0f. [Reporting paper]() Recorded evaluation configuration: {"Search Strategy":"MCTS","N":"300"}. This record does not assert independent reproduction. ### Graph2Edits Solve Rate: 88.4. Result ID: 6a03063a47f34ce924e69d09. [Reporting paper]() Recorded evaluation configuration: {"Search Strategy":"MCTS","N":"300"}. This record does not assert independent reproduction. ### LocalRetro Solve Rate: 86.7. Result ID: 6a03063a47f34ce924e69d0e. [Reporting paper]() Recorded evaluation configuration: {"Search Strategy":"MCTS","N":"100"}. This record does not assert independent reproduction. ### Graph2Edits Solve Rate: 77.3. Result ID: 6a03063a47f34ce924e69d08. [Reporting paper]() Recorded evaluation configuration: {"Search Strategy":"MCTS","N":"100"}. This record does not assert independent reproduction. ### LLM Solve Rate: 20.7. Result ID: 6a03063a47f34ce924e69d1c. [Reporting paper]() Recorded evaluation configuration: {"Search Strategy":"MCTS","N":"500"}. This record does not assert independent reproduction. ### LLM Solve Rate: 19.3. Result ID: 6a03063a47f34ce924e69d1e. [Reporting paper]() Recorded evaluation configuration: {"Search Strategy":"Retro\*","N":"300"}. This record does not assert independent reproduction. ### LLM Solve Rate: 17.3. Result ID: 6a03063a47f34ce924e69d1b. [Reporting paper]() Recorded evaluation configuration: {"Search Strategy":"MCTS","N":"300"}. This record does not assert independent reproduction. ### LLM Solve Rate: 14.7. Result ID: 6a03063a47f34ce924e69d1d. [Reporting paper]() Recorded evaluation configuration: {"Search Strategy":"Retro\*","N":"100"}. This record does not assert independent reproduction. ### LLM Solve Rate: 13.3. Result ID: 6a03063a47f34ce924e69d1f. [Reporting paper]() Recorded evaluation configuration: {"Search Strategy":"Retro\*","N":"500"}. This record does not assert independent reproduction. ### LLM Solve Rate: 12.7. Result ID: 6a03063a47f34ce924e69d1a. [Reporting paper]() Recorded evaluation configuration: {"Search Strategy":"MCTS","N":"100"}. This record does not assert independent reproduction. Page 1 of 1. This is an index page, not the full collection.