# Retrosynthesis planning on Pistachio Hard Source: [Retrosynthesis planning on Pistachio Hard]() Collection index: [llms.txt]() Data updated: 2026-05-12T10:51:49.971Z Evaluation of models performing retrosynthesis planning on the Pistachio Hard dataset, measured using Solve Rate (%). A research result applies to its stated dataset, split, metric and evaluation configuration. Compare like-for-like settings, preserve the metric's unit and direction, and distinguish paper-reported results from independent reproduction. The best result recorded here is not a claim of exhaustive, current global coverage. | Scope | Recorded value | | --- | --- | | Task | Retrosynthesis planning | | Dataset (including any stated split) | Pistachio Hard | | Metric | Solve Rate | | Unit | PERCENT | | Direction | Higher is better | | Results loaded | 30 of 30 | | Coverage | All results currently returned for this benchmark | Evaluation settings may differ between results. The original papers and recorded configurations are needed to establish comparability. A shared metric name alone does not establish an identical protocol. ## Metrics - [Solve Rate](): Higher is better; unit: PERCENT. ## Recorded results | Method | Solve Rate | Result date | Report paper | | --- | --- | --- | --- | | LLM-Syn-Planner | 87 | Not recorded | 68fa4a371e209131ce93cac1 | | LLM-Syn-Planner | 86 | Not recorded | 68fa4a371e209131ce93cac1 | | LLM-Syn-Planner | 86 | Not recorded | 68fa4a371e209131ce93cac1 | | RootAligned | 85 | Not recorded | 68fa4a371e209131ce93cac1 | | RootAligned | 85 | Not recorded | 68fa4a371e209131ce93cac1 | | LLM-Syn-Planner | 84 | Not recorded | 68fa4a371e209131ce93cac1 | | RootAligned | 83 | Not recorded | 68fa4a371e209131ce93cac1 | | Graph2Edits | 82 | Not recorded | 68fa4a371e209131ce93cac1 | | RootAligned | 82 | Not recorded | 68fa4a371e209131ce93cac1 | | RootAligned | 82 | Not recorded | 68fa4a371e209131ce93cac1 | | RootAligned | 78 | Not recorded | 68fa4a371e209131ce93cac1 | | Graph2Edits | 74 | Not recorded | 68fa4a371e209131ce93cac1 | | LLM-Syn-Planner | 74 | Not recorded | 68fa4a371e209131ce93cac1 | | LocalRetro | 72 | Not recorded | 68fa4a371e209131ce93cac1 | | LLM-Syn-Planner | 72 | Not recorded | 68fa4a371e209131ce93cac1 | | Graph2Edits | 71 | Not recorded | 68fa4a371e209131ce93cac1 | | LocalRetro | 69 | Not recorded | 68fa4a371e209131ce93cac1 | | LocalRetro | 63 | Not recorded | 68fa4a371e209131ce93cac1 | | Graph2Edits | 62 | Not recorded | 68fa4a371e209131ce93cac1 | | LocalRetro | 62 | Not recorded | 68fa4a371e209131ce93cac1 | | LocalRetro | 55 | Not recorded | 68fa4a371e209131ce93cac1 | | LocalRetro | 52 | Not recorded | 68fa4a371e209131ce93cac1 | | Graph2Edits | 41 | Not recorded | 68fa4a371e209131ce93cac1 | | Graph2Edits | 26 | Not recorded | 68fa4a371e209131ce93cac1 | | LLM | 5 | Not recorded | 68fa4a371e209131ce93cac1 | | LLM | 5 | Not recorded | 68fa4a371e209131ce93cac1 | | LLM | 4 | Not recorded | 68fa4a371e209131ce93cac1 | | LLM | 2 | Not recorded | 68fa4a371e209131ce93cac1 | | LLM | 0 | Not recorded | 68fa4a371e209131ce93cac1 | | LLM | 0 | Not recorded | 68fa4a371e209131ce93cac1 | ### LLM-Syn-Planner Solve Rate: 87. Result ID: 6a03063a47f34ce924e69d40. [Reporting paper]() [Method origin paper]() Recorded evaluation configuration: {"Backbone":"GPT-4o","N":"500"}. This record does not assert independent reproduction. ### LLM-Syn-Planner Solve Rate: 86. Result ID: 6a03063a47f34ce924e69d3f. [Reporting paper]() [Method origin paper]() Recorded evaluation configuration: {"Backbone":"GPT-4o","N":"300"}. This record does not assert independent reproduction. ### LLM-Syn-Planner Solve Rate: 86. Result ID: 6a03063a47f34ce924e69d43. [Reporting paper]() [Method origin paper]() Recorded evaluation configuration: {"Backbone":"DeepSeek-V3","N":"500"}. This record does not assert independent reproduction. ### RootAligned Solve Rate: 85. Result ID: 6a03063a47f34ce924e69d2a. [Reporting paper]() [Method origin paper]() Recorded evaluation configuration: {"Search Strategy":"MCTS","N":"300"}. This record does not assert independent reproduction. ### RootAligned Solve Rate: 85. Result ID: 6a03063a47f34ce924e69d2b. [Reporting paper]() [Method origin paper]() Recorded evaluation configuration: {"Search Strategy":"MCTS","N":"500"}. This record does not assert independent reproduction. ### LLM-Syn-Planner Solve Rate: 84. Result ID: 6a03063a47f34ce924e69d42. [Reporting paper]() [Method origin paper]() Recorded evaluation configuration: {"Backbone":"DeepSeek-V3","N":"300"}. This record does not assert independent reproduction. ### RootAligned Solve Rate: 83. Result ID: 6a03063a47f34ce924e69d29. [Reporting paper]() [Method origin paper]() Recorded evaluation configuration: {"Search Strategy":"MCTS","N":"100"}. This record does not assert independent reproduction. ### Graph2Edits Solve Rate: 82. Result ID: 6a03063a47f34ce924e69d31. [Reporting paper]() Recorded evaluation configuration: {"Search Strategy":"Retro\*","N":"500"}. This record does not assert independent reproduction. ### RootAligned Solve Rate: 82. Result ID: 6a03063a47f34ce924e69d33. [Reporting paper]() [Method origin paper]() Recorded evaluation configuration: {"Search Strategy":"Retro\*","N":"300"}. This record does not assert independent reproduction. ### RootAligned Solve Rate: 82. Result ID: 6a03063a47f34ce924e69d34. [Reporting paper]() [Method origin paper]() Recorded evaluation configuration: {"Search Strategy":"Retro\*","N":"500"}. This record does not assert independent reproduction. ### RootAligned Solve Rate: 78. Result ID: 6a03063a47f34ce924e69d32. [Reporting paper]() [Method origin paper]() Recorded evaluation configuration: {"Search Strategy":"Retro\*","N":"100"}. This record does not assert independent reproduction. ### Graph2Edits Solve Rate: 74. Result ID: 6a03063a47f34ce924e69d30. [Reporting paper]() Recorded evaluation configuration: {"Search Strategy":"Retro\*","N":"300"}. This record does not assert independent reproduction. ### LLM-Syn-Planner Solve Rate: 74. Result ID: 6a03063a47f34ce924e69d41. [Reporting paper]() [Method origin paper]() Recorded evaluation configuration: {"Backbone":"DeepSeek-V3","N":"100"}. This record does not assert independent reproduction. ### LocalRetro Solve Rate: 72. Result ID: 6a03063a47f34ce924e69d37. [Reporting paper]() Recorded evaluation configuration: {"Search Strategy":"Retro\*","N":"500"}. This record does not assert independent reproduction. ### LLM-Syn-Planner Solve Rate: 72. Result ID: 6a03063a47f34ce924e69d3e. [Reporting paper]() [Method origin paper]() Recorded evaluation configuration: {"Backbone":"GPT-4o","N":"100"}. This record does not assert independent reproduction. ### Graph2Edits Solve Rate: 71. Result ID: 6a03063a47f34ce924e69d2f. [Reporting paper]() Recorded evaluation configuration: {"Search Strategy":"Retro\*","N":"100"}. This record does not assert independent reproduction. ### LocalRetro Solve Rate: 69. Result ID: 6a03063a47f34ce924e69d36. [Reporting paper]() Recorded evaluation configuration: {"Search Strategy":"Retro\*","N":"300"}. This record does not assert independent reproduction. ### LocalRetro Solve Rate: 63. Result ID: 6a03063a47f34ce924e69d35. [Reporting paper]() Recorded evaluation configuration: {"Search Strategy":"Retro\*","N":"100"}. This record does not assert independent reproduction. ### Graph2Edits Solve Rate: 62. Result ID: 6a03063a47f34ce924e69d28. [Reporting paper]() Recorded evaluation configuration: {"Search Strategy":"MCTS","N":"500"}. This record does not assert independent reproduction. ### LocalRetro Solve Rate: 62. Result ID: 6a03063a47f34ce924e69d2e. [Reporting paper]() Recorded evaluation configuration: {"Search Strategy":"MCTS","N":"500"}. This record does not assert independent reproduction. ### LocalRetro Solve Rate: 55. Result ID: 6a03063a47f34ce924e69d2d. [Reporting paper]() Recorded evaluation configuration: {"Search Strategy":"MCTS","N":"300"}. This record does not assert independent reproduction. ### LocalRetro Solve Rate: 52. Result ID: 6a03063a47f34ce924e69d2c. [Reporting paper]() Recorded evaluation configuration: {"Search Strategy":"MCTS","N":"100"}. This record does not assert independent reproduction. ### Graph2Edits Solve Rate: 41. Result ID: 6a03063a47f34ce924e69d27. [Reporting paper]() Recorded evaluation configuration: {"Search Strategy":"MCTS","N":"300"}. This record does not assert independent reproduction. ### Graph2Edits Solve Rate: 26. Result ID: 6a03063a47f34ce924e69d26. [Reporting paper]() Recorded evaluation configuration: {"Search Strategy":"MCTS","N":"100"}. This record does not assert independent reproduction. ### LLM Solve Rate: 5. Result ID: 6a03063a47f34ce924e69d3a. [Reporting paper]() Recorded evaluation configuration: {"Search Strategy":"MCTS","N":"500"}. This record does not assert independent reproduction. ### LLM Solve Rate: 5. Result ID: 6a03063a47f34ce924e69d3d. [Reporting paper]() Recorded evaluation configuration: {"Search Strategy":"Retro\*","N":"500"}. This record does not assert independent reproduction. ### LLM Solve Rate: 4. Result ID: 6a03063a47f34ce924e69d39. [Reporting paper]() Recorded evaluation configuration: {"Search Strategy":"MCTS","N":"300"}. This record does not assert independent reproduction. ### LLM Solve Rate: 2. Result ID: 6a03063a47f34ce924e69d3c. [Reporting paper]() Recorded evaluation configuration: {"Search Strategy":"Retro\*","N":"300"}. This record does not assert independent reproduction. ### LLM Solve Rate: 0. Result ID: 6a03063a47f34ce924e69d38. [Reporting paper]() Recorded evaluation configuration: {"Search Strategy":"MCTS","N":"100"}. This record does not assert independent reproduction. ### LLM Solve Rate: 0. Result ID: 6a03063a47f34ce924e69d3b. [Reporting paper]() Recorded evaluation configuration: {"Search Strategy":"Retro\*","N":"100"}. This record does not assert independent reproduction. Page 1 of 1. 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