# Protein Sequence Generation on GB1, PhoQ, UBC9, GFP Evaluation Set

Source: [Protein Sequence Generation on GB1, PhoQ, UBC9, GFP Evaluation Set](<https://www.sota2.com/research/sota/protein-sequence-generation-on-gb1-phoq-ubc9-gfp-evaluation-set>)

Collection index: [llms.txt](<https://www.sota2.com/research/llms.txt>)

Data updated: 2026-02-26T05:45:40.496Z

Evaluation of generative models focusing on producing sequences corresponding to specific functional protein targets: GB1, PhoQ, UBC9, and GFP.

A research result applies to its stated dataset, split, metric and evaluation configuration. Compare like-for-like settings, preserve the metric's unit and direction, and distinguish paper-reported results from independent reproduction. The best result recorded here is not a claim of exhaustive, current global coverage.

| Scope | Recorded value |
| --- | --- |
| Task | Protein Sequence Generation |
| Dataset (including any stated split) | Protein Functional Evaluation GB1, PhoQ, UBC9, GFP |
| Metric | GB1 Score |
| Unit | SCALAR |
| Direction | Higher is better |
| Results loaded | 6 of 6 |
| Coverage | All results currently returned for this benchmark |

Evaluation settings may differ between results. The original papers and recorded configurations are needed to establish comparability. A shared metric name alone does not establish an identical protocol.

## Metrics

- [GB1 Score](<https://www.sota2.com/research/sota/protein-sequence-generation-on-gb1-phoq-ubc9-gfp-evaluation-set.md?metric=GB1%20Score>): Higher is better; unit: SCALAR.

- [PhoQ Score](<https://www.sota2.com/research/sota/protein-sequence-generation-on-gb1-phoq-ubc9-gfp-evaluation-set.md?metric=PhoQ%20Score>): Higher is better; unit: SCALAR.

- [UBC9 Score](<https://www.sota2.com/research/sota/protein-sequence-generation-on-gb1-phoq-ubc9-gfp-evaluation-set.md?metric=UBC9%20Score>): Higher is better; unit: SCALAR.

- [GFP Score](<https://www.sota2.com/research/sota/protein-sequence-generation-on-gb1-phoq-ubc9-gfp-evaluation-set.md?metric=GFP%20Score>): Higher is better; unit: SCALAR.

## Recorded results

| Method | GB1 Score | Result date | Report paper |
| --- | --- | --- | --- |
| InstructProtein+KPO | 0.191 | Not recorded | 68fa7a101e209131cea80e2c |
| Progen2 | 0.144 | Not recorded | 68fa7a101e209131cea80e2c |
| ProtGPT2+KPO | 0.041 | Not recorded | 68fa7a101e209131cea80e2c |
| ProtGPT2 | 0.03 | Not recorded | 68fa7a101e209131cea80e2c |
| InstructProtein | 0.03 | Not recorded | 68fa7a101e209131cea80e2c |
| Progen2+KPO | 0.024 | Not recorded | 68fa7a101e209131cea80e2c |

### InstructProtein+KPO

GB1 Score: 0.191. Result ID: 698b6c027a967eddb76e73a6.

[Reporting paper](<https://www.sota2.com/research/paper/68fa7a101e209131cea80e2c.md>)

[Method origin paper](<https://www.sota2.com/research/paper/68fa7a101e209131cea80e2c.md>)

[Implementation](<https://github.com/HICAI-ZJU/KPO>)

Recorded evaluation configuration: {"Base Model":"InstructProtein"}. This record does not assert independent reproduction.

### Progen2

GB1 Score: 0.144. Result ID: 698b6c027a967eddb76e73a3.

[Reporting paper](<https://www.sota2.com/research/paper/68fa7a101e209131cea80e2c.md>)

[Method origin paper](<https://www.sota2.com/research/paper/68fa5f2a1e209131ce9e7f7a.md>)

Recorded evaluation configuration: {"Base Model":"Progen2"}. This record does not assert independent reproduction.

### ProtGPT2+KPO

GB1 Score: 0.041. Result ID: 698b6c027a967eddb76e73a2.

[Reporting paper](<https://www.sota2.com/research/paper/68fa7a101e209131cea80e2c.md>)

[Method origin paper](<https://www.sota2.com/research/paper/68fa7a101e209131cea80e2c.md>)

[Implementation](<https://github.com/HICAI-ZJU/KPO>)

Recorded evaluation configuration: {"Base Model":"ProtGPT2"}. This record does not assert independent reproduction.

### ProtGPT2

GB1 Score: 0.03. Result ID: 698b6c027a967eddb76e73a1.

[Reporting paper](<https://www.sota2.com/research/paper/68fa7a101e209131cea80e2c.md>)

Recorded evaluation configuration: {"Base Model":"ProtGPT2"}. This record does not assert independent reproduction.

### InstructProtein

GB1 Score: 0.03. Result ID: 698b6c027a967eddb76e73a5.

[Reporting paper](<https://www.sota2.com/research/paper/68fa7a101e209131cea80e2c.md>)

[Method origin paper](<https://www.sota2.com/research/paper/68fa5f511e209131ce9e8f59.md>)

Recorded evaluation configuration: {"Base Model":"InstructProtein"}. This record does not assert independent reproduction.

### Progen2+KPO

GB1 Score: 0.024. Result ID: 698b6c027a967eddb76e73a4.

[Reporting paper](<https://www.sota2.com/research/paper/68fa7a101e209131cea80e2c.md>)

[Method origin paper](<https://www.sota2.com/research/paper/68fa7a101e209131cea80e2c.md>)

[Implementation](<https://github.com/HICAI-ZJU/KPO>)

Recorded evaluation configuration: {"Base Model":"Progen2"}. This record does not assert independent reproduction.

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