# Mutation Prediction on TCGA-CRC Source: [Mutation Prediction on TCGA-CRC]() Collection index: [llms.txt]() Data updated: 2026-02-26T05:24:39.965Z Evaluation of models predicting specific genetic mutations and molecular features (like MSI/TMB) within the TCGA Colorectal Cancer (CRC) cohort. A research result applies to its stated dataset, split, metric and evaluation configuration. Compare like-for-like settings, preserve the metric's unit and direction, and distinguish paper-reported results from independent reproduction. The best result recorded here is not a claim of exhaustive, current global coverage. | Scope | Recorded value | | --- | --- | | Task | Mutation Prediction | | Dataset (including any stated split) | TCGA-CRC | | Metric | AUC | | Unit | PERCENT | | Direction | Higher is better | | Results loaded | 24 of 24 | | Coverage | All results currently returned for this benchmark | Evaluation settings may differ between results. The original papers and recorded configurations are needed to establish comparability. A shared metric name alone does not establish an identical protocol. ## Metrics - [AUC](): Higher is better; unit: PERCENT. - [MSI](): Higher is better; unit: PERCENT. - [TMB](): Higher is better; unit: SCALAR. - [BRAF](): Higher is better; unit: PERCENT. - [ALK](): Higher is better; unit: PERCENT. - [ERBB4](): Higher is better; unit: PERCENT. - [FBXW7](): Higher is better; unit: PERCENT. - [KRAS](): Higher is better; unit: PERCENT. - [PIK3CA](): Higher is better; unit: PERCENT. - [SMAD4](): Higher is better; unit: PERCENT. - [TP53](): Higher is better; unit: PERCENT. - [PRC](): Higher is better; unit: PERCENT. ## Recorded results | Method | AUC | Result date | Report paper | | --- | --- | --- | --- | | autol | 94 | Not recorded | 68fa72771e209131cea56894 | | uncert + pcgrad | 86.7 | Not recorded | 68fa72771e209131cea56894 | | cagrad | 86.5 | Not recorded | 68fa72771e209131cea56894 | | autol + cagrad | 86.5 | Not recorded | 68fa72771e209131cea56894 | | naive | 86.4 | Not recorded | 68fa72771e209131cea56894 | | uncert + cagrad | 86.3 | Not recorded | 68fa72771e209131cea56894 | | baseline | 86.1 | Not recorded | 68fa72771e209131cea56894 | | autol + pcgrad | 86.1 | Not recorded | 68fa72771e209131cea56894 | | uncert | 86 | Not recorded | 68fa72771e209131cea56894 | | graddrop | 85.8 | Not recorded | 68fa72771e209131cea56894 | | dwa + cagrad | 85.8 | Not recorded | 68fa72771e209131cea56894 | | dwa + pcgrad | 85.6 | Not recorded | 68fa72771e209131cea56894 | | dwa + graddrop | 85.5 | Not recorded | 68fa72771e209131cea56894 | | uncert + graddrop | 85.5 | Not recorded | 68fa72771e209131cea56894 | | pcgrad | 85.4 | Not recorded | 68fa72771e209131cea56894 | | autol + graddrop | 85.3 | Not recorded | 68fa72771e209131cea56894 | | dwa | 84.2 | Not recorded | 68fa72771e209131cea56894 | | SOTA | 83 | Not recorded | 68fa72771e209131cea56894 | ### autol AUC: 94. Result ID: 69923ac73a6c3148490d78f5. [Reporting paper]() [Method origin paper]() [Implementation]() Recorded evaluation configuration: {"multi\_task":true,"weighting\_strategy":"autol"}. This record does not assert independent reproduction. ### uncert + pcgrad AUC: 86.7. Result ID: 69923ac73a6c3148490d78fd. [Reporting paper]() [Method origin paper]() [Implementation]() Recorded evaluation configuration: {"multi\_task":true,"weighting\_strategy":"uncertainty","gradient\_strategy":"pcgrad"}. This record does not assert independent reproduction. ### cagrad AUC: 86.5. Result ID: 69923ac73a6c3148490d78f8. [Reporting paper]() [Method origin paper]() [Implementation]() Recorded evaluation configuration: {"multi\_task":true,"gradient\_strategy":"cagrad"}. This record does not assert independent reproduction. ### autol + cagrad AUC: 86.5. Result ID: 69923ac73a6c3148490d7901. [Reporting paper]() [Method origin paper]() [Implementation]() Recorded evaluation configuration: {"multi\_task":true,"weighting\_strategy":"autol","gradient\_strategy":"cagrad"}. This record does not assert independent reproduction. ### naive AUC: 86.4. Result ID: 69923ac73a6c3148490d78f2. [Reporting paper]() [Method origin paper]() [Implementation]() Recorded evaluation configuration: {"multi\_task":true,"weighting\_strategy":"naive"}. This record does not assert independent reproduction. ### uncert + cagrad AUC: 86.3. Result ID: 69923ac73a6c3148490d78fe. [Reporting paper]() [Method origin paper]() [Implementation]() Recorded evaluation configuration: {"multi\_task":true,"weighting\_strategy":"uncertainty","gradient\_strategy":"cagrad"}. This record does not assert independent reproduction. ### baseline AUC: 86.1. Result ID: 69923ac73a6c3148490d78f1. [Reporting paper]() [Method origin paper]() [Implementation]() Recorded evaluation configuration: {"multi\_task":false}. This record does not assert independent reproduction. ### autol + pcgrad AUC: 86.1. Result ID: 69923ac73a6c3148490d7900. [Reporting paper]() [Method origin paper]() [Implementation]() Recorded evaluation configuration: {"multi\_task":true,"weighting\_strategy":"autol","gradient\_strategy":"pcgrad"}. This record does not assert independent reproduction. ### uncert AUC: 86. Result ID: 69923ac73a6c3148490d78f4. [Reporting paper]() [Method origin paper]() [Implementation]() Recorded evaluation configuration: {"multi\_task":true,"weighting\_strategy":"uncertainty"}. This record does not assert independent reproduction. ### graddrop AUC: 85.8. Result ID: 69923ac73a6c3148490d78f6. [Reporting paper]() [Method origin paper]() [Implementation]() Recorded evaluation configuration: {"multi\_task":true,"gradient\_strategy":"graddrop"}. This record does not assert independent reproduction. ### dwa + cagrad AUC: 85.8. Result ID: 69923ac73a6c3148490d78fb. [Reporting paper]() [Method origin paper]() [Implementation]() Recorded evaluation configuration: {"multi\_task":true,"weighting\_strategy":"dwa","gradient\_strategy":"cagrad"}. This record does not assert independent reproduction. ### dwa + pcgrad AUC: 85.6. Result ID: 69923ac73a6c3148490d78fa. [Reporting paper]() [Method origin paper]() [Implementation]() Recorded evaluation configuration: {"multi\_task":true,"weighting\_strategy":"dwa","gradient\_strategy":"pcgrad"}. This record does not assert independent reproduction. ### dwa + graddrop AUC: 85.5. Result ID: 69923ac73a6c3148490d78f9. [Reporting paper]() [Method origin paper]() [Implementation]() Recorded evaluation configuration: {"multi\_task":true,"weighting\_strategy":"dwa","gradient\_strategy":"graddrop"}. This record does not assert independent reproduction. ### uncert + graddrop AUC: 85.5. Result ID: 69923ac73a6c3148490d78fc. [Reporting paper]() [Method origin paper]() [Implementation]() Recorded evaluation configuration: {"multi\_task":true,"weighting\_strategy":"uncertainty","gradient\_strategy":"graddrop"}. This record does not assert independent reproduction. ### pcgrad AUC: 85.4. Result ID: 69923ac73a6c3148490d78f7. [Reporting paper]() [Method origin paper]() [Implementation]() Recorded evaluation configuration: {"multi\_task":true,"gradient\_strategy":"pcgrad"}. This record does not assert independent reproduction. ### autol + graddrop AUC: 85.3. Result ID: 69923ac73a6c3148490d78ff. [Reporting paper]() [Method origin paper]() [Implementation]() Recorded evaluation configuration: {"multi\_task":true,"weighting\_strategy":"autol","gradient\_strategy":"graddrop"}. This record does not assert independent reproduction. ### dwa AUC: 84.2. Result ID: 69923ac73a6c3148490d78f3. [Reporting paper]() [Method origin paper]() [Implementation]() Recorded evaluation configuration: {"multi\_task":true,"weighting\_strategy":"dwa"}. This record does not assert independent reproduction. ### SOTA AUC: 83. Result ID: 69923ac73a6c3148490d78f0. [Reporting paper]() Recorded evaluation configuration: Not recorded. This record does not assert independent reproduction. Page 1 of 1. This is an index page, not the full collection.