Macrocycle generation on PDB ID 1H00 (test)
92.5ValidityMACROGUIDE
Evaluation Results
| Method | Links | ||||
|---|---|---|---|---|---|
| MACROGUIDEBase model=MolSnapper2026.02 | 92.5 | 100 | 92.5 | 99.5 | |
| MolSnapperGuidance strategy=no guid.2026.02 | 85.8 | 100 | 85.8 | 0.3 | |
| Naive guidanceGuidance strategy=Naive, Naive guidance atom count=12 atoms2026.02 | 81.9 | 100 | 81.9 | 1.3 | |
| MolSnapperGuidance strategy=finetuned2026.02 | 79.5 | 100 | 79.5 | 18 | |
| Naive guidanceGuidance strategy=Naive, Naive guidance atom count=14 atoms2026.02 | 79.1 | 100 | 79.1 | 0 | |
| Naive guidanceGuidance strategy=Naive, Naive guidance atom count=16 atoms2026.02 | 76.3 | 100 | 76.3 | 0.3 |