# logP Optimization on ZINC-250k Source: [logP Optimization on ZINC-250k]() Collection index: [llms.txt]() Data updated: 2026-02-26T06:09:19.456Z Evaluation of model performance on optimizing the logP property using the ZINC-250k dataset. A research result applies to its stated dataset, split, metric and evaluation configuration. Compare like-for-like settings, preserve the metric's unit and direction, and distinguish paper-reported results from independent reproduction. The best result recorded here is not a claim of exhaustive, current global coverage. | Scope | Recorded value | | --- | --- | | Task | Molecular property optimization | | Dataset (including any stated split) | ZINC-250k | | Metric | logP | | Unit | SCALAR | | Direction | Higher is better | | Results loaded | 30 of 30 | | Coverage | All results currently returned for this benchmark | Evaluation settings may differ between results. The original papers and recorded configurations are needed to establish comparability. A shared metric name alone does not establish an identical protocol. ## Metrics - [logP](): Higher is better; unit: SCALAR. ## Recorded results | Method | logP | Result date | Report paper | | --- | --- | --- | --- | | Ours (GA/BGNN) | 25.26 | Not recorded | 6948d070423ea42265729ec6 | | Ours (GA/BGNN) | 24.82 | Not recorded | 6948d070423ea42265729ec6 | | Ours (GA/BGNN) | 24.09 | Not recorded | 6948d070423ea42265729ec6 | | Ours (GA/BGNN) | 19.92 | Not recorded | 6948d070423ea42265729ec6 | | Ours (GA/BGNN) | 16.32 | Not recorded | 6948d070423ea42265729ec6 | | JANUS | 16.14 | Not recorded | 6948d070423ea42265729ec6 | | JANUS | 15.96 | Not recorded | 6948d070423ea42265729ec6 | | JANUS | 15.78 | Not recorded | 6948d070423ea42265729ec6 | | JANUS | 15.6 | Not recorded | 6948d070423ea42265729ec6 | | JANUS | 15.41 | Not recorded | 6948d070423ea42265729ec6 | | Graph-GA | 15.3 | Not recorded | 6948d070423ea42265729ec6 | | Graph-GA | 15.1 | Not recorded | 6948d070423ea42265729ec6 | | Graph-GA | 15.05 | Not recorded | 6948d070423ea42265729ec6 | | Graph-GA | 14.66 | Not recorded | 6948d070423ea42265729ec6 | | Graph-GA | 14.54 | Not recorded | 6948d070423ea42265729ec6 | | Ours (VAE/GP) | 7.64 | Not recorded | 6948d070423ea42265729ec6 | | Ours (VAE/GP) | 7.59 | Not recorded | 6948d070423ea42265729ec6 | | Ours (VAE/GP) | 7.5 | Not recorded | 6948d070423ea42265729ec6 | | Ours (VAE/GP) | 7.24 | Not recorded | 6948d070423ea42265729ec6 | | Ours (VAE/GP) | 7.21 | Not recorded | 6948d070423ea42265729ec6 | | MolDQN | 6.96 | Not recorded | 6948d070423ea42265729ec6 | | MolDQN | 6.68 | Not recorded | 6948d070423ea42265729ec6 | | MolDQN | 6.53 | Not recorded | 6948d070423ea42265729ec6 | | VAE+BO | 6.49 | Not recorded | 6948d070423ea42265729ec6 | | VAE+BO | 6.44 | Not recorded | 6948d070423ea42265729ec6 | | MolDQN | 6.37 | Not recorded | 6948d070423ea42265729ec6 | | VAE+BO | 6.3 | Not recorded | 6948d070423ea42265729ec6 | | VAE+BO | 6.21 | Not recorded | 6948d070423ea42265729ec6 | | VAE+BO | 6.15 | Not recorded | 6948d070423ea42265729ec6 | | MolDQN | 6.06 | Not recorded | 6948d070423ea42265729ec6 | ### Ours (GA/BGNN) logP: 25.26. Result ID: 699a34d95698665ec4bad675. [Reporting paper]() [Method origin paper]() Recorded evaluation configuration: {"Run":"1","Generator":"GA","Surrogate":"BGNN"}. This record does not assert independent reproduction. ### Ours (GA/BGNN) logP: 24.82. Result ID: 699a34d95698665ec4bad68d. [Reporting paper]() [Method origin paper]() Recorded evaluation configuration: {"Run":"5","Generator":"GA","Surrogate":"BGNN"}. This record does not assert independent reproduction. ### Ours (GA/BGNN) logP: 24.09. Result ID: 699a34d95698665ec4bad67b. [Reporting paper]() [Method origin paper]() Recorded evaluation configuration: {"Run":"2","Generator":"GA","Surrogate":"BGNN"}. This record does not assert independent reproduction. ### Ours (GA/BGNN) logP: 19.92. Result ID: 699a34d95698665ec4bad687. [Reporting paper]() [Method origin paper]() Recorded evaluation configuration: {"Run":"4","Generator":"GA","Surrogate":"BGNN"}. This record does not assert independent reproduction. ### Ours (GA/BGNN) logP: 16.32. Result ID: 699a34d95698665ec4bad681. [Reporting paper]() [Method origin paper]() Recorded evaluation configuration: {"Run":"3","Generator":"GA","Surrogate":"BGNN"}. This record does not assert independent reproduction. ### JANUS logP: 16.14. Result ID: 699a34d95698665ec4bad671. [Reporting paper]() [Method origin paper]() Recorded evaluation configuration: {"Run":"1"}. This record does not assert independent reproduction. ### JANUS logP: 15.96. Result ID: 699a34d95698665ec4bad683. [Reporting paper]() [Method origin paper]() Recorded evaluation configuration: {"Run":"4"}. This record does not assert independent reproduction. ### JANUS logP: 15.78. Result ID: 699a34d95698665ec4bad677. [Reporting paper]() [Method origin paper]() Recorded evaluation configuration: {"Run":"2"}. This record does not assert independent reproduction. ### JANUS logP: 15.6. Result ID: 699a34d95698665ec4bad689. [Reporting paper]() [Method origin paper]() Recorded evaluation configuration: {"Run":"5"}. This record does not assert independent reproduction. ### JANUS logP: 15.41. Result ID: 699a34d95698665ec4bad67d. [Reporting paper]() [Method origin paper]() Recorded evaluation configuration: {"Run":"3"}. This record does not assert independent reproduction. ### Graph-GA logP: 15.3. Result ID: 699a34d95698665ec4bad67e. [Reporting paper]() Recorded evaluation configuration: {"Run":"3"}. This record does not assert independent reproduction. ### Graph-GA logP: 15.1. Result ID: 699a34d95698665ec4bad678. [Reporting paper]() Recorded evaluation configuration: {"Run":"2"}. This record does not assert independent reproduction. ### Graph-GA logP: 15.05. Result ID: 699a34d95698665ec4bad684. [Reporting paper]() Recorded evaluation configuration: {"Run":"4"}. This record does not assert independent reproduction. ### Graph-GA logP: 14.66. Result ID: 699a34d95698665ec4bad672. [Reporting paper]() Recorded evaluation configuration: {"Run":"1"}. This record does not assert independent reproduction. ### Graph-GA logP: 14.54. Result ID: 699a34d95698665ec4bad68a. [Reporting paper]() Recorded evaluation configuration: {"Run":"5"}. This record does not assert independent reproduction. ### Ours (VAE/GP) logP: 7.64. Result ID: 699a34d95698665ec4bad67a. [Reporting paper]() [Method origin paper]() Recorded evaluation configuration: {"Run":"2","Generator":"VAE","Surrogate":"GP"}. This record does not assert independent reproduction. ### Ours (VAE/GP) logP: 7.59. Result ID: 699a34d95698665ec4bad680. [Reporting paper]() [Method origin paper]() Recorded evaluation configuration: {"Run":"3","Generator":"VAE","Surrogate":"GP"}. This record does not assert independent reproduction. ### Ours (VAE/GP) logP: 7.5. Result ID: 699a34d95698665ec4bad68c. [Reporting paper]() [Method origin paper]() Recorded evaluation configuration: {"Run":"5","Generator":"VAE","Surrogate":"GP"}. This record does not assert independent reproduction. ### Ours (VAE/GP) logP: 7.24. Result ID: 699a34d95698665ec4bad686. [Reporting paper]() [Method origin paper]() Recorded evaluation configuration: {"Run":"4","Generator":"VAE","Surrogate":"GP"}. This record does not assert independent reproduction. ### Ours (VAE/GP) logP: 7.21. Result ID: 699a34d95698665ec4bad674. [Reporting paper]() [Method origin paper]() Recorded evaluation configuration: {"Run":"1","Generator":"VAE","Surrogate":"GP"}. This record does not assert independent reproduction. ### MolDQN logP: 6.96. Result ID: 699a34d95698665ec4bad685. [Reporting paper]() [Method origin paper]() Recorded evaluation configuration: {"Run":"4"}. This record does not assert independent reproduction. ### MolDQN logP: 6.68. Result ID: 699a34d95698665ec4bad673. [Reporting paper]() [Method origin paper]() Recorded evaluation configuration: {"Run":"1"}. This record does not assert independent reproduction. ### MolDQN logP: 6.53. Result ID: 699a34d95698665ec4bad67f. [Reporting paper]() [Method origin paper]() Recorded evaluation configuration: {"Run":"3"}. This record does not assert independent reproduction. ### VAE+BO logP: 6.49. Result ID: 699a34d95698665ec4bad67c. [Reporting paper]() [Method origin paper]() Recorded evaluation configuration: {"Run":"3"}. This record does not assert independent reproduction. ### VAE+BO logP: 6.44. Result ID: 699a34d95698665ec4bad688. [Reporting paper]() [Method origin paper]() Recorded evaluation configuration: {"Run":"5"}. This record does not assert independent reproduction. ### MolDQN logP: 6.37. Result ID: 699a34d95698665ec4bad68b. [Reporting paper]() [Method origin paper]() Recorded evaluation configuration: {"Run":"5"}. This record does not assert independent reproduction. ### VAE+BO logP: 6.3. Result ID: 699a34d95698665ec4bad682. [Reporting paper]() [Method origin paper]() Recorded evaluation configuration: {"Run":"4"}. This record does not assert independent reproduction. ### VAE+BO logP: 6.21. Result ID: 699a34d95698665ec4bad670. [Reporting paper]() [Method origin paper]() Recorded evaluation configuration: {"Run":"1"}. This record does not assert independent reproduction. ### VAE+BO logP: 6.15. Result ID: 699a34d95698665ec4bad676. [Reporting paper]() [Method origin paper]() Recorded evaluation configuration: {"Run":"2"}. This record does not assert independent reproduction. ### MolDQN logP: 6.06. Result ID: 699a34d95698665ec4bad679. [Reporting paper]() [Method origin paper]() Recorded evaluation configuration: {"Run":"2"}. This record does not assert independent reproduction. Page 1 of 1. This is an index page, not the full collection.