# Joint Paratope-Epitope Prediction on SAbDab

Source: [Joint Paratope-Epitope Prediction on SAbDab](<https://www.sota2.com/research/sota/joint-paratope-epitope-prediction-on-sabdab>)

Collection index: [llms.txt](<https://www.sota2.com/research/llms.txt>)

Data updated: 2026-02-26T05:57:18.074Z

Evaluation of models performing joint prediction of paratope and epitope regions using the SAbDab dataset, measured by AUC, AUPR, and MCC for both components.

A research result applies to its stated dataset, split, metric and evaluation configuration. Compare like-for-like settings, preserve the metric's unit and direction, and distinguish paper-reported results from independent reproduction. The best result recorded here is not a claim of exhaustive, current global coverage.

| Scope | Recorded value |
| --- | --- |
| Task | Joint Paratope-Epitope Prediction |
| Dataset (including any stated split) | SAbDab |
| Metric | Paratope AUC |
| Unit | PERCENT |
| Direction | Higher is better |
| Results loaded | 4 of 4 |
| Coverage | All results currently returned for this benchmark |

Evaluation settings may differ between results. The original papers and recorded configurations are needed to establish comparability. A shared metric name alone does not establish an identical protocol.

## Metrics

- [Paratope AUC](<https://www.sota2.com/research/sota/joint-paratope-epitope-prediction-on-sabdab.md?metric=Paratope%20AUC>): Higher is better; unit: PERCENT.

- [Paratope AUPR](<https://www.sota2.com/research/sota/joint-paratope-epitope-prediction-on-sabdab.md?metric=Paratope%20AUPR>): Higher is better; unit: PERCENT.

- [Paratope MCC](<https://www.sota2.com/research/sota/joint-paratope-epitope-prediction-on-sabdab.md?metric=Paratope%20MCC>): Higher is better; unit: PERCENT.

- [Epitope AUC](<https://www.sota2.com/research/sota/joint-paratope-epitope-prediction-on-sabdab.md?metric=Epitope%20AUC>): Higher is better; unit: PERCENT.

- [Epitope AUPR](<https://www.sota2.com/research/sota/joint-paratope-epitope-prediction-on-sabdab.md?metric=Epitope%20AUPR>): Higher is better; unit: PERCENT.

- [Epitope MCC](<https://www.sota2.com/research/sota/joint-paratope-epitope-prediction-on-sabdab.md?metric=Epitope%20MCC>): Higher is better; unit: PERCENT.

## Recorded results

| Method | Paratope AUC | Result date | Report paper |
| --- | --- | --- | --- |
| MIPE | 89.4 | Not recorded | 68fa5f5b1e209131ce9e9318 |
| Epi-EPMP | 87.8 | Not recorded | 68fa5f5b1e209131ce9e9318 |
| MIPE | 86.3 | Not recorded | 68fa5f5b1e209131ce9e9318 |
| Honda et al. | 85.4 | Not recorded | 68fa5f5b1e209131ce9e9318 |

### MIPE

Paratope AUC: 89.4. Result ID: 698bc4817a967eddb7713590.

[Reporting paper](<https://www.sota2.com/research/paper/68fa5f5b1e209131ce9e9318.md>)

[Method origin paper](<https://www.sota2.com/research/paper/68fa5f5b1e209131ce9e9318.md>)

[Implementation](<https://github.com/WangZhiwei9/MIPE>)

Recorded evaluation configuration: {"Structure Source":"Experimental"}. This record does not assert independent reproduction.

### Epi-EPMP

Paratope AUC: 87.8. Result ID: 698bc4817a967eddb771358f.

[Reporting paper](<https://www.sota2.com/research/paper/68fa5f5b1e209131ce9e9318.md>)

[Method origin paper](<https://www.sota2.com/research/paper/68fa5f171e209131ce9e76e0.md>)

Recorded evaluation configuration: Not recorded. This record does not assert independent reproduction.

### MIPE

Paratope AUC: 86.3. Result ID: 698bc4817a967eddb7713591.

[Reporting paper](<https://www.sota2.com/research/paper/68fa5f5b1e209131ce9e9318.md>)

[Method origin paper](<https://www.sota2.com/research/paper/68fa5f5b1e209131ce9e9318.md>)

[Implementation](<https://github.com/WangZhiwei9/MIPE>)

Recorded evaluation configuration: {"Structure Source":"AlphaFold2"}. This record does not assert independent reproduction.

### Honda et al.

Paratope AUC: 85.4. Result ID: 698bc4817a967eddb771358e.

[Reporting paper](<https://www.sota2.com/research/paper/68fa5f5b1e209131ce9e9318.md>)

Recorded evaluation configuration: Not recorded. This record does not assert independent reproduction.

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